{"id":10321,"date":"2026-03-27T08:21:54","date_gmt":"2026-03-27T12:21:54","guid":{"rendered":"https:\/\/www.curingheartdisease.com\/?p=10321"},"modified":"2026-07-16T10:47:59","modified_gmt":"2026-07-16T14:47:59","slug":"%d8%a7%d9%84%d8%b3%d9%85-%d8%a7%d9%84%d8%ae%d9%81%d9%8a-%d9%81%d9%8a-%d8%b4%d8%b1%d9%8a%d8%ad%d8%a9-%d8%a7%d9%84%d9%84%d8%ad%d9%85-%d9%83%d9%8a%d9%81-%d8%aa%d8%ad%d9%81%d8%b2-%d8%a8%d9%83%d8%aa%d9%8a","status":"publish","type":"post","link":"https:\/\/www.curingheartdisease.com\/ar\/the-hidden-toxin-in-your-steak-how-gut-bacteria-drive-heart-disease\/","title":{"rendered":"\u0627\u0644\u0633\u0645 \u0627\u0644\u062e\u0641\u064a \u0641\u064a \u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u0644\u062d\u0645: \u0643\u064a\u0641 \u062a\u062d\u0641\u0632 \u0628\u0643\u062a\u064a\u0631\u064a\u0627 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628"},"content":{"rendered":"<h2>\u0627\u0644\u062c\u0632\u064a\u0621 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(\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u062a\u0627 \u0627\u0644\u0623\u0645\u0639\u0627\u0621)\u060c \u0648\u0639\u0644\u0645 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629 \u0644\u0644\u0645\u0636\u064a\u0641 (\u0627\u0644\u0643\u0628\u062f \u0648\u0627\u0644\u0643\u0644\u0649). \u064a\u0642\u062f\u0645 \u0647\u0630\u0627 \u0627\u0644\u062a\u0642\u0631\u064a\u0631 \u062f\u0631\u0627\u0633\u0629 \u0645\u062a\u0639\u0645\u0642\u0629 \u0648\u0634\u0627\u0645\u0644\u0629 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062e\u0628\u0631\u0627\u0621 \u0644\u0645\u062d\u0648\u0631 TMAO\u060c \u062d\u064a\u062b \u064a\u062d\u0644\u0644 \u0628\u0646\u064a\u062a\u0647 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629\u060c \u0648\u0627\u0644\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 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\u0648\u0627\u0644\u0625\u0646\u0641\u0644\u0627\u0645\u0627\u0633\u0648\u0645 NLRP3<\/h4>\n<p>\u064a\u0639\u0645\u0644 TMAO \u0643\u0645\u062d\u0641\u0632 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0648\u0639\u0627\u0626\u064a \u0648\u0627\u0644\u062e\u0644\u0644 \u0627\u0644\u0648\u0638\u064a\u0641\u064a \u0641\u064a \u0627\u0644\u0628\u0637\u0627\u0646\u0629\u060c \u0648\u0643\u0644\u0627\u0647\u0645\u0627 \u062e\u0637\u0648\u062a\u0627\u0646 \u0645\u0628\u0643\u0631\u062a\u0627\u0646 \u0645\u0647\u0645\u062a\u0627\u0646 \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u0644\u0648\u064a\u062d\u0627\u062a. \u0648\u0645\u0646 \u0627\u0644\u0645\u0633\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u064f\u0646\u0627\u0642\u0634 \u0643\u062b\u064a\u0631\u064b\u0627 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0633\u064a\u0627\u0642 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0640 <strong>\u0627\u0644\u062c\u0633\u062f \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a NLRP3<\/strong>.<\/p>\n<p>\u062a\u062a\u0636\u0645\u0646 \u0627\u0644\u0622\u0644\u064a\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u062e\u0644\u0644\u0627\u064b \u0648\u0638\u064a\u0641\u064a\u064b\u0651\u0627 \u0641\u064a \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0627 \u0648\u062a\u0631\u0627\u0643\u0645 \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u064a\u0629 \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u064a\u0629 (mtROS). \u0648\u0642\u062f \u0623\u064f\u0641\u064a\u062f \u0623\u0646 \u0645\u0627\u062f\u0629 TMAO \u062a\u062b\u0628\u0637 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0625\u0646\u0632\u064a\u0645 \u062f\u064a\u0623\u0633\u064a\u062a\u064a\u0644\u0627\u0632 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\u0627\u0644\u062b\u064a\u0648\u0631\u064a\u062f\u0648\u0643\u0633\u064a\u0646 (TXNIP)<\/strong>, \u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0628\u062f\u0648\u0631\u0647 \u0625\u0644\u0649 \u062a\u0643\u0648\u064a\u0646 \u0625\u0646\u0641\u0644\u0627\u0645\u0627\u0633\u0648\u0645 NLRP3. \u062b\u0645 \u064a\u0624\u062f\u064a \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0625\u0646\u0641\u0644\u0627\u0645\u0627\u0633\u0648\u0645 \u0625\u0644\u0649 \u0627\u0646\u0642\u0633\u0627\u0645 \u0628\u0631\u0648-\u0643\u0627\u0633\u0628\u0627\u0632-1 \u0648\u0625\u0637\u0644\u0627\u0642 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0633\u0628\u0628\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628 <strong>\u0625\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646-1 \u0628\u064a\u062a\u0627<\/strong> \u0648 <strong>IL-18<\/strong>.<\/p>\n<table>\n<thead>\n<tr>\n<td><strong>\u0645\u0633\u0627\u0631 \u0627\u0644\u0625\u0634\u0627\u0631\u0629<\/strong><\/td>\n<td><strong>\u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u062e\u0644\u0648\u064a \u0644\u0640 TMAO<\/strong><\/td>\n<td><strong>\u0627\u0644\u0627\u0639\u062a\u0644\u0627\u0644\u0627\u062a \u0627\u0644\u0646\u0627\u062a\u062c\u0629<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>NLRP3 \/ TXNIP<\/td>\n<td>\u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0625\u0646\u0641\u0644\u0627\u0645\u0627\u0633\u0648\u0645 \u0648\u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a (IL-1\u03b2\u060c IL-18)<\/td>\n<td>\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0628\u0637\u0627\u0646\u0629\u060c \u0625\u0635\u0627\u0628\u0629 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629<\/td>\n<\/tr>\n<tr>\n<td>\u0639\u0627\u0645\u0644 \u0646\u0648\u0648\u064a \u0643\u0627\u0628\u0627 \u0628\u064a<\/td>\n<td>\u0632\u064a\u0627\u062f\u0629 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\u0627\u0644\u0623\u0633\u0627\u0633 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u0644\u0647\u0630\u0627 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0641\u064a \u062a\u0639\u062f\u064a\u0644 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u062f\u0627\u062e\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 (<strong>Ca2+<\/strong>) \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a. \u064a\u064f\u0633\u0647\u0651\u0644 TMAO \u0625\u0641\u0631\u0627\u0632 <strong>Ca2+<\/strong> \u0645\u0646 \u0645\u062e\u0632\u0648\u0646\u0627\u062a \u0627\u0644\u0635\u0641\u0627\u0626\u062d \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062a\u0643\u062a\u0644 \u0648\u062a\u0633\u0631\u064a\u0639 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u062c\u0644\u0637\u0627\u062a \u0641\u064a \u0638\u0631\u0648\u0641 \u0627\u0644\u0642\u0635 \u0627\u0644\u0639\u0627\u0644\u064a. \u0648\u0645\u0646 \u0627\u0644\u0645\u0647\u0645 \u0627\u0644\u0625\u0634\u0627\u0631\u0629 \u0625\u0644\u0649 \u0623\u0646 \u0625\u0632\u0627\u0644\u0629 \u0642\u062f\u0631\u0629 \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c \u0645\u0627\u062f\u0629 TMA \u0641\u064a \u0627\u0644\u0646\u0638\u0645 \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a\u0629 \u062a\u0642\u0636\u064a \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u0638\u0627\u0647\u0631\u064a \u0627\u0644\u062e\u062b\u0627\u0631\u064a \u0627\u0644\u0645\u062a\u0632\u0627\u064a\u062f\u060c \u0645\u0645\u0627 \u064a\u062f\u0639\u0645 \u0641\u0643\u0631\u0629 \u0623\u0646 \u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u0645 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0639\u0645\u0644 \u0643\u0645\u0646\u0638\u0645 \u0644\u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u062a\u062e\u062b\u0631 \u0627\u0644\u062c\u0647\u0627\u0632\u064a.<\/p>\n<h3><strong>\u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629: TMAO \u0643\u0639\u0644\u0627\u0645\u0629 \u062a\u0646\u0628\u0624\u064a\u0629 \u0639\u0627\u0644\u0645\u064a\u0629<\/strong><\/h3>\n<p>\u0645\u0646\u0630 \u0635\u062f\u0648\u0631 \u0627\u0644\u062a\u0642\u0631\u064a\u0631 \u0627\u0644\u0623\u0648\u0644\u064a \u0627\u0644\u0630\u064a \u0631\u0628\u0637 \u0628\u064a\u0646 \u0645\u0627\u062f\u0629 TMAO \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0641\u064a \u0639\u0627\u0645 2011\u060c \u0642\u0627\u0645\u062a \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0623\u062a\u0631\u0627\u0628\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629 \u0648\u0627\u0644\u062a\u062d\u0644\u064a\u0644\u0627\u062a \u0627\u0644\u062a\u0644\u0648\u064a\u0629 \u0628\u062a\u0642\u064a\u064a\u0645 \u0645\u0627\u062f\u0629 TMAO \u0628\u0627\u0639\u062a\u0628\u0627\u0631\u0647\u0627 \u0639\u0627\u0645\u0644 \u062a\u0646\u0628\u0624 \u0645\u0633\u062a\u0642\u0644 \u0628\u062d\u062f\u0648\u062b \u0627\u0644\u0623\u062d\u062f\u0627\u062b \u0627\u0644\u0633\u0644\u0628\u064a\u0629 \u0627\u0644\u0643\u0628\u0631\u0649 \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0627\u0644\u062f\u0645\u0627\u063a\u064a\u0629 (MACCE \u0623\u0648 MACE).<\/p>\n<h4>\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0645\u0646 \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0633\u0628\u0627\u0628<\/h4>\n<p>\u0642\u062f\u0645\u062a \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u0627\u062a \u0627\u0644\u062a\u0644\u0648\u064a\u0629 \u0648\u0627\u0633\u0639\u0629 \u0627\u0644\u0646\u0637\u0627\u0642 \u0627\u0644\u062a\u064a \u0634\u0645\u0644\u062a \u0639\u0634\u0631\u0627\u062a \u0627\u0644\u0622\u0644\u0627\u0641 \u0645\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0623\u062f\u0644\u0629 \u0643\u0645\u064a\u0629 \u0639\u0644\u0649 \u0648\u062c\u0648\u062f \u0635\u0644\u0629 \u0628\u064a\u0646 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a TMAO \u0641\u064a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0633\u0644\u0628\u064a\u0629. \u0648\u0642\u062f \u062a\u0648\u0635\u0644 \u0623\u062d\u062f \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u0627\u062a \u0627\u0644\u062a\u0644\u0648\u064a\u0629 \u0627\u0644\u062a\u064a \u064a\u064f\u0633\u062a\u0634\u0647\u062f \u0628\u0647\u0627 \u0643\u062b\u064a\u0631\u064b\u0627\u060c \u0648\u0627\u0644\u0630\u064a \u0634\u0645\u0644 14 \u062f\u0631\u0627\u0633\u0629 (15,662 \u0645\u0634\u0627\u0631\u0643\u064b\u0627)\u060c \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0641\u0639\u0629 \u0644\u0640 TMAO \u0641\u064a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u062a\u0631\u062a\u0628\u0637 \u0628\u0646\u0633\u0628\u0629 \u062e\u0637\u0631 (HR) \u062a\u0628\u0644\u063a <strong>1.91<\/strong> \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0645\u0646 \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0623\u0642\u0644.<\/p>\n<table>\n<thead>\n<tr>\n<td><strong>\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/strong><\/td>\n<td><strong>\u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0648\u0646 \/ \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a<\/strong><\/td>\n<td><strong>\u0627\u0644\u062a\u0642\u062f\u064a\u0631 \u0627\u0644\u0625\u062d\u0635\u0627\u0626\u064a (\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u062e\u0627\u0637\u0631\/\u0646\u0633\u0628\u0629 \u0627\u0644\u062e\u0637\u0648\u0631\u0629)<\/strong><\/td>\n<td><strong>\u0641\u0627\u0635\u0644 \u0627\u0644\u062b\u0642\u0629 (95%)<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0645\u0646 \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0633\u0628\u0627\u0628<\/td>\n<td>15,662 \u0645\u0634\u0627\u0631\u0643\u064b\u0627<\/td>\n<td>\u0645\u0639\u062f\u0644 \u0627\u0644\u0636\u0631\u0628\u0627\u062a: 1.91<\/td>\n<td>1.40-2.61<\/td>\n<\/tr>\n<tr>\n<td>MACCE \/ MACE<\/td>\n<td>13,944 \u0645\u0634\u0627\u0631\u0643\u064b\u0627<\/td>\n<td>\u0645\u0639\u062f\u0644 \u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u0628\u0634\u0631\u064a: 1.67<\/td>\n<td>1.33-2.11<\/td>\n<\/tr>\n<tr>\n<td>\u0627\u0644\u0623\u062d\u062f\u0627\u062b \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629<\/td>\n<td>10,245 \u0645\u0634\u0627\u0631\u0643\u064b\u0627<\/td>\n<td>\u0645\u0639\u062f\u0644 \u0627\u0644\u0636\u0631\u0628\u0627\u062a: 1.23<\/td>\n<td>1.07-1.42<\/td>\n<\/tr>\n<tr>\n<td>\u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a (\u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644)<\/td>\n<td>218 \u0645\u0634\u0627\u0631\u0643\u064b\u0627 (\u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0633\u0648\u0621 \u0627\u0644\u062a\u063a\u0630\u064a\u0629)<\/td>\n<td>\u0645\u0639\u062f\u0644 \u0627\u0644\u0636\u063a\u0637: 2.01<\/td>\n<td>1.23-3.31<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u0623\u0634\u0627\u0631\u062a \u062a\u062d\u0644\u064a\u0644\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u062c\u0631\u0639\u0629 \u0648\u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u062a\u0631\u062a\u0641\u0639 \u062a\u062f\u0631\u064a\u062c\u064a\u064b\u0627 \u0645\u0639 \u0627\u0631\u062a\u0641\u0627\u0639 \u062a\u0631\u0643\u064a\u0632\u0627\u062a TMAO. \u0648\u0641\u064a \u0623\u062d\u062f \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u0627\u062a \u0627\u0644\u062a\u0644\u0648\u064a\u0629\u060c \u0643\u0644 <strong>10 \u0645\u064a\u0643\u0631\u0648\u0645\u0648\u0644\/\u0644\u062a\u0631<\/strong> \u0627\u0631\u062a\u0628\u0637 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u0649 TMAO \u0641\u064a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0628\u0632\u064a\u0627\u062f\u0629 \u062a\u0628\u0644\u063a \u062a\u0642\u0631\u064a\u0628\u064b\u0627 <strong>7.6%<\/strong> \u0627\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u062e\u0637\u0631 \u0627\u0644\u0646\u0633\u0628\u064a \u0644\u0644\u0648\u0641\u0627\u0629 \u0644\u0623\u064a \u0633\u0628\u0628 \u0643\u0627\u0646. \u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u062a\u0638\u0644 \u0647\u0630\u0647 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a \u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0629 \u0628\u0639\u062f \u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u0639\u0645\u0631 \u0648\u0627\u0644\u062c\u0646\u0633 \u0648\u0645\u0624\u0634\u0631 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 \u0648\u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u0647\u0646\u064a \u0645\u0646\u062e\u0641\u0636 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 (LDL) \u0648\u062d\u0627\u0644\u0629 \u0627\u0644\u062a\u062f\u062e\u064a\u0646\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0623\u0646 \u0645\u0627\u062f\u0629 TMAO \u0642\u062f \u062a\u062d\u0645\u0644 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u062a\u0646\u0628\u0624\u064a\u0629 \u0644\u0627 \u062a\u0646\u0639\u0643\u0633 \u0628\u0627\u0644\u0643\u0627\u0645\u0644 \u0641\u064a \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u062e\u0637\u0631 \u0627\u0644\u062a\u0642\u0644\u064a\u062f\u064a\u0629 \u0648\u062d\u062f\u0647\u0627.<\/p>\n<h3>\u0642\u0635\u0648\u0631 \u0627\u0644\u0642\u0644\u0628 \u0648\u0625\u0639\u0627\u062f\u0629 \u062a\u0634\u0643\u064a\u0644 \u0627\u0644\u0642\u0644\u0628<\/h3>\n<p>\u0641\u064a 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\u0639\u0645\u0644\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644 \u0628\u0633\u0628\u0628 \u0638\u0647\u0648\u0631 \u0627\u0644\u0645\u0642\u0627\u0648\u0645\u0629\u060c \u0648\u0627\u0644\u0623\u0636\u0631\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0644\u062d\u0642 \u0628\u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u0645\u060c \u0648\u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0627\u0644\u0627\u0631\u062a\u062f\u0627\u062f.<\/li>\n<li><strong>\u0627\u0644\u0628\u0631\u0648\u0628\u064a\u0648\u062a\u064a\u0643 \u0648\u0627\u0644\u0628\u0631\u064a\u0628\u064a\u0648\u062a\u064a\u0643:<\/strong> \u0628\u0639\u0636 \u0633\u0644\u0627\u0644\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u0628\u064a\u0648\u062a\u064a\u0643\u060c \u0648\u0644\u0627 \u0633\u064a\u0645\u0627 <strong>\u0628\u064a\u0641\u064a\u062f\u0648\u0628\u0627\u0643\u062a\u064a\u0631\u064a\u0648\u0645<\/strong> \u0648 <strong>\u0627\u0644\u0644\u0627\u0643\u062a\u0648\u0628\u0627\u0633\u064a\u0644\u0627\u0633<\/strong>, \u060c \u0648\u0642\u062f \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u0623\u0644\u064a\u0627\u0641 \u0627\u0644\u0628\u0631\u064a\u0628\u0627\u064a\u0648\u062a\u064a\u0629 \u0645\u062b\u0644 \u0627\u0644\u0625\u064a\u0646\u0648\u0644\u064a\u0646 \u0642\u062f\u0631\u0629 \u0645\u062d\u062a\u0645\u0644\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062e\u0641\u064a\u0641 \u0645\u0646 \u0627\u0633\u062a\u062c\u0627\u0628\u0627\u062a TMAO \u0628\u0639\u062f \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u0637\u0639\u0627\u0645\u060c \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0645\u0633\u062a\u0645\u062f\u0629 \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062a\u064a \u0623\u062c\u0631\u064a\u062a \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631 \u0644\u0627 \u062a\u0632\u0627\u0644 \u0645\u062d\u062f\u0648\u062f\u0629 \u0648\u063a\u064a\u0631 \u0645\u062a\u062c\u0627\u0646\u0633\u0629.<\/li>\n<\/ul>\n<h3>\u0627\u0644\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629: \u0627\u0644\u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u062f\u0648\u0627\u0626\u064a<\/h3>\n<p>\u062a\u0631\u0643\u0632\u062a \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0644\u062e\u0641\u0636 \u0645\u0633\u062a\u0648\u0649 TMAO \u0639\u0644\u0649 \u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u0625\u0646\u0632\u064a\u0645\u0627\u062a \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0646\u062a\u062c TMA\u060c \u0648\u064a\u0641\u0636\u0644 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0630\u0644\u0643 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0631\u0643\u0628\u0627\u062a \u063a\u064a\u0631 \u0642\u0627\u062a\u0644\u0629 \u062a\u0642\u062a\u0635\u0631 \u0641\u0639\u0627\u0644\u064a\u062a\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0623\u0645\u0639\u0627\u0621.<\/p>\n<h4>\u0645\u062b\u0628\u0637\u0627\u062a \u0625\u0646\u0632\u064a\u0645 TMA \u0644\u064a\u0627\u0632<\/h4>\n<p>\u064a\u064f\u0639\u062f \u062a\u062b\u0628\u064a\u0637 \u0625\u0646\u0632\u064a\u0645\u0627\u062a \u00abTMA \u0644\u064a\u0627\u0632\u00bb \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0629 \u0627\u0644\u0645\u0633\u0627\u0631 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0623\u0643\u062b\u0631 \u0648\u0627\u0639\u062f\u0629\u060c \u0648\u0644\u0627 \u0633\u064a\u0645\u0627 <strong>\u0642\u0637\u0639 C\/D<\/strong> \u0627\u0644\u062c\u0647\u0627\u0632. \u0648\u0639\u0644\u0649 \u0639\u0643\u0633 \u0627\u0644\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u062d\u064a\u0648\u064a\u0629\u060c \u0635\u064f\u0645\u0645\u062a \u0647\u0630\u0647 \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0644\u062a\u062b\u0628\u064a\u0637 \u0646\u0634\u0627\u0637 \u0627\u0644\u0625\u0646\u0632\u064a\u0645\u0627\u062a \u062f\u0648\u0646 \u0642\u062a\u0644 \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627\u060c \u0645\u0645\u0627 \u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u0636\u063a\u0637 \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0626\u064a \u0627\u0644\u0630\u064a \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0638\u0647\u0648\u0631 \u0627\u0644\u0645\u0642\u0627\u0648\u0645\u0629.<\/p>\n<ul>\n<li><strong>3,3-\u062b\u0646\u0627\u0626\u064a \u0645\u064a\u062b\u064a\u0644-1-\u0628\u0648\u062a\u0627\u0646\u0648\u0644 (DMB):<\/strong> \u0645\u0631\u0643\u0628 \u0645\u0634\u0627\u0628\u0647 \u0647\u064a\u0643\u0644\u064a\u064b\u0627 \u0644\u0644\u0643\u0648\u0644\u064a\u0646\u060c \u064a\u062a\u0648\u0627\u062c\u062f \u0628\u0643\u0645\u064a\u0627\u062a \u0636\u0626\u064a\u0644\u0629 \u0641\u064a \u0628\u0639\u0636 \u0627\u0644\u0623\u0637\u0639\u0645\u0629. \u064a\u0639\u0645\u0644 DMB \u0643\u0645\u062b\u0628\u0637 \u062a\u0646\u0627\u0641\u0633\u064a \u0644\u0625\u0646\u0632\u064a\u0645\u0627\u062a TMA \u0627\u0644\u0644\u064a\u0627\u0632 \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0629. \u0641\u064a \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629\u060c \u064a\u0642\u0644\u0644 DMB \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a TMAO \u0641\u064a \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627\u060c \u0648\u064a\u0645\u0646\u0639 \u062a\u0643\u0648\u0651\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0631\u063a\u0648\u064a\u0629\u060c \u0648\u064a\u062e\u0641\u0641 \u0645\u0646 \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646.<\/li>\n<li><strong>\u0647\u0627\u0644\u0648\u0645\u064a\u062b\u064a\u0644\u0643\u0648\u0644\u064a\u0646\u0627\u062a (IMC \u0648 FMC):<\/strong> \u064a\u064f\u0639\u062f \u0643\u0644\u0648\u0631\u064a\u062f \u0627\u0644\u064a\u0648\u062f \u0648\u0627\u0644\u0645\u064a\u062b\u064a\u0644 (IMC) \u0648\u0643\u0644\u0648\u0631\u064a\u062f \u0627\u0644\u0641\u0644\u0648\u0631 \u0648\u0627\u0644\u0645\u064a\u062b\u064a\u0644 (FMC) \u0645\u062b\u0628\u0637\u0627\u062a \u0645\u0646 \u0627\u0644\u062c\u064a\u0644 \u0627\u0644\u062b\u0627\u0646\u064a \u062a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0622\u0644\u064a\u0629 \u0627\u0644\u0639\u0645\u0644\u060c \u0648\u0642\u062f \u0623\u0638\u0647\u0631\u062a \u0641\u0639\u0627\u0644\u064a\u0629 \u0623\u0643\u0628\u0631 \u0628\u0643\u062b\u064a\u0631 \u0645\u0646 DMB \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629. \u062a\u0634\u064a\u0631 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0625\u0644\u0649 \u0623\u0646 IMC \u064a\u0645\u0643\u0646\u0647 \u062e\u0641\u0636 \u0645\u0633\u062a\u0648\u064a\u0627\u062a TMAO \u0644\u0641\u062a\u0631\u0627\u062a \u0637\u0648\u064a\u0644\u0629\u060c \u0648\u0625\u0639\u0627\u062f\u0629 \u062a\u0646\u0638\u064a\u0645 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0644\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0641\u064a \u0627\u0644\u062c\u0633\u0645\u060c \u0648\u062a\u0642\u0644\u064a\u0644 \u0627\u062d\u062a\u0645\u0627\u0644\u064a\u0629 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u062e\u062b\u0631\u0627\u062a \u062f\u0648\u0646 \u0632\u064a\u0627\u062f\u0629 \u0648\u0627\u0636\u062d\u0629 \u0641\u064a \u0632\u0645\u0646 \u0627\u0644\u0646\u0632\u064a\u0641 \u0641\u064a \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629.<\/li>\n<\/ul>\n<table>\n<thead>\n<tr>\n<td><strong>\u0641\u0626\u0629 \u0627\u0644\u0645\u062b\u0628\u0637\u0627\u062a<\/strong><\/td>\n<td><strong>\u0627\u0644\u0645\u0631\u0643\u0628 \u0627\u0644\u0631\u0626\u064a\u0633\u064a<\/strong><\/td>\n<td><strong>\u0622\u0644\u064a\u0629 \u0627\u0644\u0639\u0645\u0644<\/strong><\/td>\n<td><strong>\u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \/ \u0627\u0644\u0628\u062d\u062b\u064a\u0629<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u0645\u062b\u0628\u0637 \u062a\u0646\u0627\u0641\u0633\u064a<\/td>\n<td>DMB<\/td>\n<td>\u0645\u0631\u0643\u0628 \u0645\u0634\u0627\u0628\u0647 \u0644\u0644\u0643\u0648\u0644\u064a\u0646\u061b \u064a\u062b\u0628\u0637 \u0646\u0634\u0627\u0637 CutC\/D<\/td>\n<td>\u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a<\/td>\n<\/tr>\n<tr>\n<td>\u0627\u0644\u0631\u0643\u064a\u0632\u0629 \u0627\u0644\u0627\u0646\u062a\u062d\u0627\u0631\u064a\u0629<\/td>\n<td>IMC \/ FMC<\/td>\n<td>\u064a\u062b\u0628\u0637 \u0625\u0646\u0632\u064a\u0645 CutC\/D \u0628\u0634\u0643\u0644 \u0644\u0627 \u0631\u062c\u0639\u0629 \u0641\u064a\u0647<\/td>\n<td>\u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a<\/td>\n<\/tr>\n<tr>\n<td>\u0645\u062b\u0628\u0637 \u0643\u0628\u062f\u064a<\/td>\n<td>\u0645\u062b\u0628\u0637\u0627\u062a FMO3<\/td>\n<td>\u062a\u0645\u0646\u0639 \u0627\u0644\u0643\u062a\u0644 \u062d\u062f\u0648\u062b \u0623\u0643\u0633\u062f\u0629 TMA<\/td>\n<td>\u0645\u0642\u064a\u062f \u0628\u0633\u0628\u0628 \u0627\u0644\u0633\u0645\u064a\u0629 \/ \u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0645\u0631\u0636 \u062a\u0631\u064a\u0645\u064a\u062b\u064a\u0644\u0627\u0645\u064a\u0646\u0648\u0631\u064a\u0627<\/td>\n<\/tr>\n<tr>\n<td>\u0645\u064f\u0639\u062f\u0650\u0651\u0644 \u063a\u064a\u0631 \u0645\u0628\u0627\u0634\u0631<\/td>\n<td>\u0643\u0627\u0646\u0627\u062c\u0644\u064a\u0641\u0644\u0648\u0632\u064a\u0646<\/td>\n<td>\u0642\u062f \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u063a\u064a\u064a\u0631 \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a \u0627\u0644\u0623\u064a\u0636\u064a\u0629 \u0628\u064a\u0646 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0648\u0627\u0644\u0645\u0636\u064a\u0641<\/td>\n<td>\u0645\u0639\u062a\u0645\u062f \u0633\u0631\u064a\u0631\u064a\u064b\u0651\u0627\u060c \u0648\u0644\u0643\u0646 \u0644\u064a\u0633 \u0643\u0639\u0644\u0627\u062c \u0645\u062e\u0635\u0635 \u0644\u0640 TMAO<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u0625\u0646\u0632\u064a\u0645 \u0627\u0644\u0645\u0636\u064a\u0641<\/h4>\n<p>\u062a\u062b\u0628\u064a\u0637 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0643\u0628\u062f <strong>FMO3<\/strong> \u0647\u0646\u0627\u0643 \u0637\u0631\u064a\u0642\u0629 \u0646\u0638\u0631\u064a\u0629 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\u0648. \u0647\u0640.\u060c \u0647\u0627\u0632\u0646 \u0633. \u0644. \u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0645\u0633\u0627\u0647\u0645 \u0644\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u0645 \u0627\u0644\u0645\u0639\u0648\u064a \u0641\u064a \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629. <em>\u0645\u062c\u0644\u0629 \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/em>. 2014\u061b 124(10):4204-4211. doi:10.1172\/JCI72331<\/li>\n<li>Wang Z\u060c Klipfell E\u060c Bennett BJ\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u0633\u0647\u0645 \u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0627\u0644\u0641\u0648\u0633\u0641\u0627\u062a\u064a\u062f\u064a\u0644\u0643\u0648\u0644\u064a\u0646 \u0641\u064a \u0641\u0644\u0648\u0631\u0627 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0641\u064a \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629. <em>\u0627\u0644\u0637\u0628\u064a\u0639\u0629<\/em>. 2011\u061b 472(7341):57-63. doi:10.1038\/nature09922<\/li>\n<li>\u062a\u0634\u0646 \u0625\u0645. \u0625\u0644\u060c \u062a\u0634\u0648 \u0625\u0643\u0633. \u0625\u062a\u0634\u060c \u0631\u0627\u0646 \u0625\u0644\u060c \u0644\u0627\u0646\u063a \u0625\u062a\u0634. \u062f\u064a\u060c \u064a\u064a \u0625\u0644\u060c \u0645\u064a \u0625\u0645. \u062a\u064a. \u064a\u064f\u062d\u062f\u062b \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0623\u0645\u064a\u0646-\u0625\u0646-\u0623\u0648\u0643\u0633\u064a\u062f \u0627\u0644\u062a\u0647\u0627\u0628\u064b\u0627 \u0648\u0639\u0627\u0626\u064a\u064b\u0651\u0627 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u0646\u0634\u064a\u0637 \u0625\u0646\u0641\u0644\u0627\u0645\u0627\u0633\u0648\u0645 NLRP3 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0645\u0633\u0627\u0631 \u0627\u0644\u0625\u0634\u0627\u0631\u0629 SIRT3-SOD2-mtROS. <em>\u0627\u0644\u0645\u062c\u0644\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u0642\u0644\u0628<\/em>. 2017\u061b 6(9):e006347. \u0646\u064f\u0634\u0631 \u0641\u064a 4 \u0633\u0628\u062a\u0645\u0628\u0631 2017. doi:10.1161\/JAHA.117.006347<\/li>\n<li>\u062a\u0627\u0646\u063a \u0648. \u0647. \u0648.\u060c \u0644\u064a\u0645\u064a\u062a\u0631 \u0631. \u0646.\u060c \u062c\u0646\u0633\u0646 \u0628. \u0646.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u062a\u0631\u064a\u0645\u064a\u062b\u064a\u0644\u0627\u0645\u064a\u0646 <em>N<\/em>-\u0627\u0644\u0623\u0643\u0633\u064a\u062f \u0648\u0627\u0644\u0645\u0633\u062a\u0642\u0644\u0628\u0627\u062a \u0630\u0627\u062a \u0627\u0644\u0635\u0644\u0629 \u0627\u0644\u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0627\u0644\u0623\u0645\u0639\u0627\u0621\u060c \u0648\u062a\u0637\u0648\u0631 \u062d\u0627\u0644\u0627\u062a \u0642\u0635\u0648\u0631 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0633\u0643\u0627\u0646\u064a\u0629 \u0627\u0644\u0645\u0642\u064a\u0645\u0629 \u0641\u064a \u0627\u0644\u0645\u062c\u062a\u0645\u0639 \u0627\u0644\u0645\u062d\u0644\u064a. <em>\u062f\u0648\u0631\u0629 \u0642\u0635\u0648\u0631 \u0627\u0644\u0642\u0644\u0628<\/em>. 2024\u061b 17(8):e011569. doi:10.1161\/CIRCHEARTFAILURE.124.011569<\/li>\n<li>\u0631\u0648\u0628\u0631\u062a\u0633 \u0623. \u0628.\u060c \u063a\u0648 \u0625\u0643\u0633\u060c \u0628\u0648\u0641\u0627 \u062c. \u0623.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u062a\u0637\u0648\u064a\u0631 \u0639\u0644\u0627\u062c \u063a\u064a\u0631 \u0645\u0645\u064a\u062a \u064a\u0633\u062a\u0647\u062f\u0641 \u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0644\u062a\u062b\u0628\u064a\u0637 \u0627\u062d\u062a\u0645\u0627\u0644\u064a\u0629 \u062a\u0643\u0648\u0651\u0646 \u0627\u0644\u062c\u0644\u0637\u0627\u062a. <em>\u0646\u064a\u062a \u0645\u064a\u062f<\/em>. 2018\u061b 24(9):1407-1417. doi:10.1038\/s41591-018-0128-1<\/li>\n<li>Koeth RA\u060c Levison BS\u060c Culley MK\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u064f\u0639\u062f \u03b3-\u0628\u0648\u062a\u064a\u0631\u0648\u0628\u064a\u062a\u064a\u0646 \u0645\u0627\u062f\u0629 \u0648\u0633\u064a\u0637\u0629 \u0645\u0633\u0628\u0628\u0629 \u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a \u0627\u0644\u0645\u0639\u0648\u064a \u0644\u0644\u0640 L-\u0643\u0627\u0631\u0646\u064a\u062a\u064a\u0646 \u0625\u0644\u0649 TMAO. <em>Cell Metab<\/em>. 2014\u061b 20(5):799-812. doi:10.1016\/j.cmet.2014.10.006<\/li>\n<li>\u062a\u0634\u0648 \u0633\u064a \u0625\u064a\u060c \u0643\u0648\u062f\u064a\u0644 \u0625\u0645 \u0625\u064a\u0647. \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0623\u0645\u064a\u0646-\u0625\u0646-\u0623\u0648\u0643\u0633\u064a\u062f: \u0635\u062f\u064a\u0642 \u0623\u0645 \u0639\u062f\u0648 \u0623\u0645 \u0645\u062c\u0631\u062f \u0636\u062d\u064a\u0629 \u0641\u064a \u0635\u0631\u0627\u0639 \u0628\u064a\u0646 \u0637\u0631\u0641\u064a\u0646\u061f. <em>\u0645\u062c\u0644\u0629 \u00abTrends Endocrinol Metab\u00bb<\/em>. 2017\u061b 28(2):121-130. doi:10.1016\/j.tem.2016.10.005<\/li>\n<li>Wang Z\u060c Tang WHW\u060c O\u2019Connell T\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u0645\u0633\u062a\u0648\u064a\u0627\u062a N-\u0623\u0648\u0643\u0633\u064a\u062f \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0627\u0644\u0623\u0645\u064a\u0646 \u0641\u064a \u0627\u0644\u062f\u0645 \u0628\u0639\u062f \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u0623\u0633\u0645\u0627\u0643 \u0623\u0648 \u0627\u0644\u0645\u0623\u0643\u0648\u0644\u0627\u062a \u0627\u0644\u0628\u062d\u0631\u064a\u0629. <em>\u0627\u0644\u0645\u062c\u0644\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0644\u0644\u062a\u063a\u0630\u064a\u0629<\/em>. 2022\u061b61(5):2357-2364. doi:10.1007\/s00394-022-02803-4<\/li>\n<li>Schiattarella GG\u060c Sannino A\u060c Toscano E\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u0627\u0644\u0645\u0633\u062a\u0642\u0644\u0628 \u00ab\u062a\u0631\u064a\u0645\u064a\u062b\u064a\u0644\u0627\u0645\u064a\u0646-N-\u0623\u0648\u0643\u0633\u064a\u062f\u00bb \u0627\u0644\u0646\u0627\u062a\u062c \u0639\u0646 \u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0643\u0645\u0624\u0634\u0631 \u062d\u064a\u0648\u064a \u0644\u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629: \u0645\u0631\u0627\u062c\u0639\u0629 \u0645\u0646\u0647\u062c\u064a\u0629 \u0648\u062a\u062d\u0644\u064a\u0644 \u062a\u0644\u0648\u064a \u0644\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u062c\u0631\u0639\u0629 \u0648\u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629. <em>\u0645\u062c\u0644\u0629 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629<\/em>. 2017\u061b38(39):2948-2956. doi:10.1093\/eurheartj\/ehx342<\/li>\n<li>\u0644\u064a \u0634\u060c \u062c\u064a\u0646\u063a \u062c\u060c \u062a\u0634\u0627\u0648 \u062c\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u064f\u0624\u062f\u064a \u0646-\u0623\u0648\u0643\u0633\u064a\u062f \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0627\u0644\u0623\u0645\u064a\u0646 \u0625\u0644\u0649 \u062a\u0641\u0627\u0642\u0645 \u0627\u0644\u062a\u0644\u064a\u0641 \u0627\u0644\u0642\u0644\u0628\u064a \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u0646\u0634\u064a\u0637 \u0625\u0646\u0641\u0644\u0627\u0645\u0627\u0633\u0648\u0645 NLRP3. <em>\u0639\u0644\u0645 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0623\u0645\u0627\u0645\u064a\u0629<\/em>. 2019\u061b10:866. \u0646\u064f\u0634\u0631 \u0641\u064a 9 \u064a\u0648\u0644\u064a\u0648 2019. doi:10.3389\/fphys.2019.00866<\/li>\n<li>Hu X\u060c Ren H\u060c Cao Y. \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0646-\u0623\u0643\u0633\u064a\u062f \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0627\u0644\u0623\u0645\u064a\u0646 \u0648\u062d\u062f\u0648\u062b \u0627\u0644\u0633\u0643\u062a\u0629 \u0627\u0644\u062f\u0645\u0627\u063a\u064a\u0629 \u0627\u0644\u0625\u0642\u0641\u0627\u0631\u064a\u0629: \u062a\u062d\u0644\u064a\u0644 \u062a\u0644\u0648\u064a \u0648\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u0639\u0634\u0648\u0627\u0626\u064a \u0627\u0644\u0645\u0646\u062f\u0644\u064a. <em>\u0645\u062c\u0644\u0629 BMC \u0644\u0644\u0637\u0628 \u0627\u0644\u0639\u0635\u0628\u064a<\/em>. 2023\u061b 23(1):413. \u0646\u064f\u0634\u0631 \u0641\u064a 21 \u0646\u0648\u0641\u0645\u0628\u0631 2023. doi:10.1186\/s12883-023-03458-2<\/li>\n<li>Koeth RA\u060c Levison BS\u060c Culley MK\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u064f\u0639\u062f \u03b3-\u0628\u0648\u062a\u064a\u0631\u0648\u0628\u064a\u062a\u064a\u0646 \u0645\u0627\u062f\u0629 \u0648\u0633\u064a\u0637\u0629 \u0645\u0633\u0628\u0628\u0629 \u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a \u0627\u0644\u0645\u0639\u0648\u064a \u0644\u0644\u0640 L-\u0643\u0627\u0631\u0646\u064a\u062a\u064a\u0646 \u0625\u0644\u0649 TMAO. <em>Cell Metab<\/em>. 2014\u061b 20(5):799-812. doi:10.1016\/j.cmet.2014.10.006<\/li>\n<li>\u0628\u0627\u062b\u0627\u0643 \u0628.\u060c \u0647\u064a\u0644\u0633\u0644\u064a \u0631.\u0646.\u060c \u0628\u0631\u0627\u0648\u0646 \u0623.\u0644.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u0624\u062f\u064a \u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a \u0627\u0644\u0635\u063a\u064a\u0631\u0629 \u0644\u0646\u0634\u0627\u0637 \u0625\u0646\u0632\u064a\u0645 \u00ab\u0643\u0648\u0644\u064a\u0646 \u062a\u0631\u064a\u0645\u064a\u062b\u064a\u0644\u0627\u0645\u064a\u0646 \u0644\u064a\u0632\u00bb \u0641\u064a \u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0625\u0644\u0649 \u062a\u063a\u064a\u064a\u0631 \u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0648\u0627\u0644\u0623\u062d\u0645\u0627\u0636 \u0627\u0644\u0635\u0641\u0631\u0627\u0648\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0645\u0636\u064a\u0641. <em>\u0627\u0644\u0645\u062c\u0644\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0639\u0644\u0645 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0623\u0639\u0636\u0627\u0621: \u0641\u0633\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u062f\u0648\u0631\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629<\/em>. 2020\u061b 318(6): H1474-H1486. doi:10.1152\/ajpheart.00584.2019<\/li>\n<li>\u0644\u064a \u0625\u0643\u0633 \u0625\u0633\u060c \u0639\u0628\u064a\u062f \u0633\u060c \u0643\u0644\u064a\u0646\u063a\u0646\u0628\u0631\u063a \u0631\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u0646\u064a\u062a\u0631\u0648\u0643\u0633\u064a\u062f \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0627\u0644\u0623\u0645\u064a\u0646 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u062a\u0627 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0641\u064a \u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0627\u062a \u0627\u0644\u062a\u0627\u062c\u064a\u0629 \u0627\u0644\u062d\u0627\u062f\u0629: \u0645\u0624\u0634\u0631 \u062a\u0646\u0628\u0624\u064a \u0644\u062d\u062f\u0648\u062b \u0623\u062d\u062f\u0627\u062b \u0642\u0644\u0628\u064a\u0629 \u0648\u0639\u0627\u0626\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u064a\u062a\u062c\u0627\u0648\u0632 \u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u062e\u0637\u0631 \u0627\u0644\u062a\u0642\u0644\u064a\u062f\u064a\u0629. <em>\u0645\u062c\u0644\u0629 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629<\/em>. 2017\u061b38(11):814-824. doi:10.1093\/eurheartj\/ehw582<\/li>\n<li>\u0633\u062a\u0627\u0628\u0633 \u062c. \u0631.\u060c \u0647\u0627\u0648\u0633 \u062c. \u0623.\u060c \u0623\u0648\u0643 \u0623. \u062c.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u0631\u062a\u0641\u0639 \u0645\u0633\u062a\u0648\u0649 \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0623\u0645\u064a\u0646-N-\u0623\u0648\u0643\u0633\u064a\u062f \u0641\u064a \u0645\u0635\u0644 \u0627\u0644\u062f\u0645 \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u0627\u0644\u0641\u0634\u0644 \u0627\u0644\u0643\u0644\u0648\u064a \u0627\u0644\u0645\u0632\u0645\u0646\u060c \u0648\u064a\u0631\u062a\u0628\u0637 \u0628\u0645\u062f\u0649 \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0627\u0644\u062a\u0627\u062c\u064a\u0629. <em>\u0627\u0644\u0645\u062c\u0644\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u062c\u0645\u0639\u064a\u0629 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0643\u0644\u0649<\/em>. 2016\u061b 27(1):305-313. doi:10.1681\/ASN.2014111063<\/li>\n<li>\u062a\u0627\u0646\u063a \u0648. \u0647\u0640.\u060c \u0647\u0627\u0632\u0646 \u0633. \u0644. \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u0645\u060c \u0648\u0623\u0643\u0633\u064a\u062f \u0646-\u062a\u0631\u064a\u0645\u064a\u062b\u064a\u0644\u0627\u0645\u064a\u0646\u060c \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0623\u064a\u0636\u064a\u0629. <em>\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u062a\u0631\u062c\u0645\u0629<\/em>. 2017\u061b179:108-115. doi:10.1016\/j.trsl.2016.07.007<\/li>\n<li>\u0647\u064a\u064a\u0627\u0646\u0632\u0627 \u064a.\u060c \u0645\u0627 \u0648.\u060c \u062f\u064a\u062f\u0648\u0646\u0627\u062a\u0648 \u062c. \u0623.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u0627\u0644\u062a\u063a\u064a\u0631\u0627\u062a \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0645\u062f\u0649 \u0641\u064a \u0645\u0633\u062a\u0642\u0644\u0628 \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0627\u0644\u0645\u0639\u0648\u064a\u0629 \u00ab\u0623\u0643\u0633\u064a\u062f \u0627\u0644\u0646\u064a\u062a\u0631\u0648\u062c\u064a\u0646 \u062b\u0644\u0627\u062b\u064a \u0627\u0644\u0645\u064a\u062b\u064a\u0644 \u0623\u0645\u064a\u0646\u00bb \u0648\u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u062a\u0627\u062c\u064a\u0629. <em>\u0645\u062c\u0644\u0629 \u0627\u0644\u0643\u0644\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628<\/em>. 2020\u061b75(7):763-772. doi:10.1016\/j.jacc.2019.11.060<\/li>\n<li>\u0648\u0627\u0646\u063a \u0632.\u060c \u0631\u0648\u0628\u0631\u062a\u0633 \u0623. \u0628.\u060c \u0628\u0648\u0641\u0627 \u062c. \u0623.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u0627\u0644\u062a\u062b\u0628\u064a\u0637 \u063a\u064a\u0631 \u0627\u0644\u0645\u0645\u064a\u062a \u0644\u0625\u0646\u062a\u0627\u062c \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0623\u0645\u064a\u0646 \u0645\u0646 \u0642\u0628\u0644 \u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0644\u0639\u0644\u0627\u062c \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646. <em>\u0627\u0644\u062e\u0644\u064a\u0629<\/em>. 2015\u061b 163(7):1585-1595. doi:10.1016\/j.cell.2015.11.055<\/li>\n<li>\u0641\u0648\u063a\u062a \u0625\u0646. \u0625\u0645\u060c \u0631\u0648\u0645\u0627\u0646\u0648 \u0643. \u0623\u060c \u062f\u0627\u0631\u0633\u062a \u0628. \u0641\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u064a\u0631\u062a\u0641\u0639 \u0645\u0633\u062a\u0648\u0649 \u0645\u0633\u062a\u0642\u0644\u0628 \u00ab\u0623\u0643\u0633\u064a\u062f \u0627\u0644\u0646\u064a\u062a\u0631\u0648\u062c\u064a\u0646 \u062b\u0644\u0627\u062b\u064a \u0627\u0644\u0645\u064a\u062b\u064a\u0644 \u0623\u0645\u064a\u0646\u00bb \u0627\u0644\u0645\u0634\u062a\u0642 \u0645\u0646 \u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u062a\u0627 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0641\u064a \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631. <em>\u0639\u0644\u0627\u062c \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631<\/em>. 2018\u061b 10(1):124. \u0646\u064f\u0634\u0631 \u0641\u064a 22 \u062f\u064a\u0633\u0645\u0628\u0631 2018. doi:10.1186\/s13195-018-0451-2<\/li>\n<li>\u062c\u064a \u0625\u0643\u0633\u060c \u062a\u064a\u0627\u0646 \u0625\u0644\u060c \u0646\u064a\u0648 \u0625\u0633\u060c \u064a\u0627\u0648 \u0625\u0633\u060c \u0643\u0648 \u0633\u064a. \u064a\u064f\u0639\u0632\u0632 \u0646-\u0623\u0648\u0643\u0633\u064a\u062f \u062a\u0631\u064a\u0645\u064a\u062b\u064a\u0644\u0627\u0645\u064a\u0646 \u0639\u0645\u0644\u064a\u0629 \u0625\u0632\u0627\u0644\u0629 \u0627\u0644\u0645\u064a\u0627\u0644\u064a\u0646 \u0641\u064a \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0627\u0644\u062a\u0644\u0642\u0627\u0626\u064a \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0639\u0632\u064a\u0632 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0628\u064a\u0631\u0648\u0628\u062a\u0648\u0633\u064a\u0633 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0623\u0648\u0644\u064a\u063a\u0648\u062f\u064a\u0646\u062f\u0631\u0648\u0633\u064a\u062a\u064a\u0629. <em>\u0645\u062c\u0644\u0629 \u00abFronts in Aging Neuroscience\u00bb<\/em>. 2022\u061b14:963876. \u0646\u064f\u0634\u0631 \u0641\u064a 22 \u0623\u063a\u0633\u0637\u0633 2022. doi:10.3389\/fnagi.2022.963876<\/li>\n<li>\u0623\u0648\u0628\u064a\u062f \u0631.\u060c \u0645\u0648\u0631 \u0644.\u060c \u0648\u0627\u064a\u062a \u0628. \u0623.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u00ab\u0646-\u0623\u0648\u0643\u0633\u064a\u062f \u062b\u0644\u0627\u062b\u064a \u0645\u064a\u062b\u064a\u0644 \u0627\u0644\u0623\u0645\u064a\u0646\u00bb \u0641\u064a \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0648\u0627\u0644\u062f\u0645\u0627\u063a\u064a\u0629 \u0648\u0627\u0644\u0643\u0644\u0648\u064a\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a: \u0645\u0631\u0627\u062c\u0639\u0629 \u0634\u0627\u0645\u0644\u0629 \u0644\u0644\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u0627\u0644\u0645\u0646\u0647\u062c\u064a\u0629 \u0648\u0627\u0644\u062a\u062d\u0644\u064a\u0644\u0627\u062a \u0627\u0644\u062a\u0644\u0648\u064a\u0629 \u0627\u0644\u0645\u0646\u0634\u0648\u0631\u0629. <em>\u0627\u0644\u0645\u063a\u0630\u064a\u0627\u062a \u0648\u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629<\/em>. 2025\u061b35(8):103908. doi:10.1016\/j.numecd.2025.103908<\/li>\n<li>\u0632\u064a\u0641\u064a \u062f.\u060c \u0643\u0648\u0631\u064a\u0645 \u062a.\u060c \u0632\u0645\u0648\u0631\u0627 \u0646.\u060c \u0648\u0622\u062e\u0631\u0648\u0646. \u0627\u0644\u062a\u063a\u0630\u064a\u0629 \u0627\u0644\u0645\u062e\u0635\u0635\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062a\u0646\u0628\u0624 \u0628\u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0627\u062a \u0627\u0644\u062c\u0644\u0627\u064a\u0633\u064a\u0645\u064a\u0629. <em>\u0627\u0644\u062e\u0644\u064a\u0629<\/em>. 2015\u061b 163(5):1079-1094. doi:10.1016\/j.cell.2015.11.001<\/li>\n<\/ol>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u0627\u0644\u062c\u0632\u064a\u0621 \u0627\u0644\u0630\u064a \u064a\u0631\u0628\u0637 \u0623\u0645\u0639\u0627\u0621\u0643 \u0628\u0642\u0644\u0628\u0643: 5 \u062d\u0642\u0627\u0626\u0642 \u0645\u062f\u0647\u0634\u0629 \u062d\u0648\u0644 TMAO. \u0627\u0644\u062a\u062a\u0627\u0628\u0639 \u0627\u0644\u0623\u064a\u0636\u064a \u063a\u064a\u0631 \u0627\u0644\u0645\u0631\u0626\u064a: \u0645\u062d\u0648\u0631 \u0643\u0627\u0626\u0646\u0627\u062a\u064a-\u0645\u062a\u0639\u062f\u062f. \u0643\u0627\u0646 \u064a\u064f\u0646\u0638\u0631 \u0625\u0644\u0649 \u0635\u062d\u0629 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0630\u0627\u062a \u0645\u0631\u0629 \u0645\u0646 \u0645\u0646\u0638\u0648\u0631 \u062c\u064a\u0646\u064a \u0628\u062d\u062a\u060c \u0628\u064a\u062f \u0623\u0646 \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0646\u0627\u0634\u0626\u0629 \u0641\u064a \u0645\u062d\u0648\u0631 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0648\u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u062a\u0643\u0634\u0641 \u0623\u0646 \u0641\u0633\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u062c\u0633\u0645\u0646\u0627 \u064a\u062a\u0645 \u0625\u062f\u0627\u0631\u062a\u0647\u0627 \u0628\u0648\u0627\u0633\u0637\u0629 \u062a\u062a\u0627\u0628\u0639 \u201c\u0643\u0627\u0626\u0646\u0627\u062a\u064a-\u0645\u062a\u0639\u062f\u062f\u201d.<\/p>","protected":false},"author":16,"featured_media":10325,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[216,259,231,223],"tags":[],"class_list":["post-10321","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diet-and-nutrition","category-gut-and-molecular","category-inflammation","category-plaque-arteries-and-disease"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The Hidden Toxin in Your Steak: How Gut Bacteria Drive Heart Disease - The Premiere Heart Health Education Platform<\/title>\n<meta name=\"description\" content=\"The Molecule Linking Your Gut to Your Heart: 5 Surprising Truths About TMAO. The Invisible Metabolic Relay: A Meta-Organismal Axis. 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