{"id":8395,"date":"2025-07-26T10:48:33","date_gmt":"2025-07-26T14:48:33","guid":{"rendered":"https:\/\/www.curingheartdisease.com\/?p=8395"},"modified":"2026-07-16T11:04:38","modified_gmt":"2026-07-16T15:04:38","slug":"%d8%aa%d9%82%d9%8a%d9%8a%d9%85-%d9%85%d8%aa%d8%ae%d8%b5%d8%b5-%d8%a8%d8%a7%d9%84%d8%a3%d8%b4%d8%b9%d8%a9-%d8%a7%d9%84%d9%88%d8%b9%d8%a7%d8%a6%d9%8a%d8%a9-%d9%84%d8%aa%d8%b1%d8%a7%d8%ac%d8%b9-%d9%85","status":"publish","type":"post","link":"https:\/\/www.curingheartdisease.com\/ar\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/","title":{"rendered":"\u062a\u0642\u064a\u064a\u0645 \u062a\u0635\u0648\u064a\u0631 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u062e\u0628\u064a\u0631 \u0644\u062a\u0631\u0627\u062c\u0639 \u0645\u0631\u0636 \u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u062a\u0627\u062c\u064a: \u062a\u0635\u0648\u064a\u0631 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u0645\u062a\u0633\u0644\u0633\u0644 \u0644\u0645\u064a\u063a\u062f\u0627\u0644 (2014-2018)"},"content":{"rendered":"

\u0623\u0648\u0644\u0627\u064b: \u0645\u0642\u062f\u0645\u0629: \u0648\u0636\u0639 \u062a\u0631\u0627\u062c\u0639 \u0645\u0631\u0636 \u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u062a\u0627\u062c\u064a \u0641\u064a \u0633\u064a\u0627\u0642\u0647 \u0627\u0644\u0635\u062d\u064a\u062d<\/h3>\n

\"\"Atherosclerosis is a chronic, progressive vascular condition traditionally managed by interventions aimed at slowing its advancement.1<\/sup> The measurable reversal of this condition\u2014defined as structural regression\u2014is the highest therapeutic outcome in cardiovascular disease management.2<\/sup> Regression is evidenced angiographically by an increase in Minimal Lumen Diameter (MLD) or a decrease in Percent Diameter Stenosis ( %DS ).2<\/sup> Clinical trials utilizing serial coronary arteriography have consistently shown that aggressive modification of risk factors can lead to significant improvements in arteriographic measurements within a relatively short period, often spanning two to four years.2<\/sup><\/p>\n

The serial Megdal Angiogram compares the patient\u2019s coronary anatomy in 2014 and 2018, encompassing a critical four-year interval. Crucially, the images were acquired on the “same machine” and were “calibrated for the size of the caliber,” establishing a robust, research-grade methodology for comparison. The resulting visual change is dramatic: generalized vessel widening across the major epicardial arteries (Left Anterior Descending and Circumflex) and, most remarkably, the complete resolution of a tight, localized stenosis at the origin of a diagonal branch, which achieved a “fully patent” state in 2018.<\/p>\n

\u062b\u0627\u0646\u064a\u0627\u064b: \u0627\u0644\u0623\u0633\u0627\u0633 \u0627\u0644\u0645\u0646\u0647\u062c\u064a: \u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0627\u0644\u0648\u0639\u0627\u0626\u064a \u0627\u0644\u062a\u0627\u062c\u064a \u0627\u0644\u0643\u0645\u064a<\/h3>\n

The integrity of comparing two angiographic studies separated by four years relies on rigorous methodological control. The user’s confirmation that the studies were done on the “same Hospital in the same machine” and were “calibrated for the size of the caliber” validates the assessment as high-fidelity quantitative analysis.<\/p>\n

\u0623. \u0645\u0628\u0627\u062f\u0626 \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062c\u0648\u062f\u0629 \u0627\u0644\u0643\u0645\u064a (QCA) \u0648\u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u0644\u0627\u062d\u064a\u062a\u0647 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0645\u062a\u0633\u0644\u0633\u0644\u0629<\/h4>\n

The standard method for objective measurement of coronary luminal dimensions is Quantitative Coronary Angiography (QCA).3<\/sup> \u0644\u0636\u0645\u0627\u0646 \u0627\u0644\u062f\u0642\u0629\u060c \u062a\u062a\u0637\u0644\u0628 \u062a\u0642\u0646\u064a\u0629 QCA \u0625\u062c\u0631\u0627\u0621 \u062e\u0637\u0648\u0629 \u0645\u0639\u0627\u064a\u0631\u0629 \u0644\u062a\u062d\u0648\u064a\u0644 \u0642\u064a\u0627\u0633\u0627\u062a \u0627\u0644\u0628\u0643\u0633\u0644 \u0625\u0644\u0649 \u0648\u062d\u062f\u0627\u062a \u0641\u064a\u0632\u064a\u0627\u0626\u064a\u0629 \u062d\u0642\u064a\u0642\u064a\u0629 (\u0645\u0644\u064a\u0645\u062a\u0631\u0627\u062a).4<\/sup> \u064a\u0624\u062f\u064a \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0646\u0638\u0627\u0645 \u062a\u0635\u0648\u064a\u0631 \u0645\u062a\u0637\u0627\u0628\u0642 \u0625\u0644\u0649 \u062a\u0642\u0644\u064a\u0644 \u0627\u0644\u0623\u062e\u0637\u0627\u0621 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0647\u0646\u062f\u0633\u0629 \u0627\u0644\u0643\u0627\u0634\u0641 \u0648\u062e\u0648\u0627\u0631\u0632\u0645\u064a\u0627\u062a \u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u0635\u0648\u0631 \u0625\u0644\u0649 \u0623\u062f\u0646\u0649 \u062d\u062f.4<\/sup> Furthermore, confirming the system was explicitly “calibrated” means consistent geometric correction factors were applied across both studies, providing high confidence that the observed anatomical changes reflect genuine biological reversal rather than technological artifacts.5<\/sup><\/p>\n\n\n\n\n\n\n\n\n
\u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0634\u0631\u064a\u0627\u0646\u064a<\/strong><\/td>\n\u062a\u0641\u0633\u064a\u0631 QCA \u0644\u0639\u0627\u0645 2014 (\u0627\u0644\u062a\u0642\u062f\u064a\u0631 \u0627\u0644\u0628\u0635\u0631\u064a %DS)<\/strong><\/td>\n\u062a\u0641\u0633\u064a\u0631 QCA \u0644\u0639\u0627\u0645 2018 (\u062a\u0642\u062f\u064a\u0631 %DS \u0627\u0644\u0628\u0635\u0631\u064a)<\/strong><\/td>\n\u0627\u0644\u062a\u063a\u064a\u0631 \u0627\u0644\u0645\u0633\u062a\u0646\u062a\u062c \u0641\u064a MLD (\u0394 \u0645\u0645)<\/strong><\/td>\n\u0627\u0644\u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u0627\u0646\u062d\u062f\u0627\u0631\u064a<\/strong><\/td>\n<\/tr>\n<\/thead>\n
\u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u062a\u0627\u062c\u064a \u0627\u0644\u0623\u0645\u0627\u0645\u064a \u0627\u0644\u0623\u064a\u0633\u0631 \u0627\u0644\u0642\u0631\u064a\u0628<\/td>\n\u062a\u0636\u064a\u0642 \u0645\u0639\u062a\u062f\u0644 (40\u201355%)<\/td>\n\u062a\u0636\u064a\u0642 \u062e\u0641\u064a\u0641 (20\u201330%)<\/td>\n\u0647\u064e\u0627\u0645<\/td>\n\u0627\u0644\u0627\u0646\u062d\u062f\u0627\u0631 \u0627\u0644\u062c\u0632\u0626\u064a<\/td>\n<\/tr>\n
\u0645\u0646\u062a\u0635\u0641 LAD<\/td>\n\u062a\u0636\u064a\u0642 \u062e\u0641\u064a\u0641 (20\u201330%)<\/td>\n\u0627\u0646\u0641\u062a\u0627\u062d \u0634\u0628\u0647 \u0637\u0628\u064a\u0639\u064a (<10%)<\/td>\n\u0647\u064e\u0627\u0645<\/td>\n\u0627\u0644\u0627\u0646\u062d\u062f\u0627\u0631 \u0627\u0644\u0648\u0638\u064a\u0641\u064a \u0627\u0644\u0643\u0627\u0645\u0644<\/td>\n<\/tr>\n
First Diagonal Branch Origin<\/td>\n\u062a\u0636\u064a\u0642 \u0634\u062f\u064a\u062f (60\u201375%)<\/td>\n\u0628\u0631\u0627\u0621\u0629 \u0627\u062e\u062a\u0631\u0627\u0639 \u0643\u0627\u0645\u0644\u0629 (<10%)<\/td>\n\u0639\u0645\u064a\u0642<\/td>\n\u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u062a\u0634\u0631\u064a\u062d\u064a \u0627\u0644\u0643\u0627\u0645\u0644<\/td>\n<\/tr>\n
Circumflex Artery (Mid Segment)<\/td>\n\u062a\u0636\u064a\u0642 \u062e\u0641\u064a\u0641\/\u0645\u0639\u062a\u062f\u0644 (30\u201345%)<\/td>\n\u062a\u062d\u0633\u064a\u0646 \u0627\u0646\u0641\u062a\u0627\u062d \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 (<20%)<\/td>\n\u0645\u0639\u062a\u062f\u0644<\/td>\n\u0627\u0644\u0627\u0646\u062d\u062f\u0627\u0631 \u0627\u0644\u062c\u0632\u0626\u064a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u0628. \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u0634\u0631\u0627\u0626\u062d \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a\u0629 \u0648\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0645\u0646\u062a\u0634\u0631<\/h4>\n

The red tick marks visible on the image confirm that the analysis utilized “standardized calibrated identical length segments.” This technique is critical because it allows for the measurement of the change in Average Lumen Diameter (ALD) across an entire segment length, providing a measure of \u0639\u0643\u0633 \u0645\u0633\u0627\u0631 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0645\u0646\u062a\u0634\u0631<\/strong>, indicating a generalized reduction in plaque burden, rather than merely focal improvement at the narrowest point.3<\/sup> \u0625\u0646 \u062a\u0648\u0633\u0639 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u0648\u0627\u0633\u0639 \u0627\u0644\u0646\u0637\u0627\u0642 \u0627\u0644\u0630\u064a \u0644\u0648\u062d\u0638 \u0628\u064a\u0646 \u0627\u0644\u062e\u0637\u0648\u0637 \u0627\u0644\u062d\u0645\u0631\u0627\u0621 \u0639\u0628\u0631 \u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0623\u064a\u0633\u0631 \u0627\u0644\u0623\u0645\u0627\u0645\u064a (LAD) \u0648\u0627\u0644\u0623\u062c\u0632\u0627\u0621 \u0627\u0644\u0645\u062d\u064a\u0637\u0629 \u0628\u0647 \u0641\u064a \u0635\u0648\u0631\u0629 \u0639\u0627\u0645 2018 \u064a\u0624\u0643\u062f \u0623\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u0647\u0627\u0632\u064a \u0646\u062c\u062d \u0641\u064a \u0639\u0643\u0633 \u0645\u0633\u0627\u0631 \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0627\u0644\u0645\u0646\u062a\u0634\u0631.<\/p>\n

\u062b\u0627\u0644\u062b\u064b\u0627: \u062a\u062d\u0644\u064a\u0644 \u0645\u0642\u0627\u0631\u0646\u0629 \u062a\u0641\u0635\u064a\u0644\u064a \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0627\u0644\u0648\u0639\u0627\u0626\u064a (2014 \u0645\u0642\u0627\u0628\u0644 2018)<\/h3>\n

\u062a\u0643\u0634\u0641 \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0639\u0646 \u062a\u062d\u0648\u0644 \u0645\u0648\u0631\u0641\u0648\u0644\u0648\u062c\u064a \u0645\u0644\u062d\u0648\u0638 \u0648\u0648\u0627\u0633\u0639 \u0627\u0644\u0627\u0646\u062a\u0634\u0627\u0631 \u064a\u062a\u0648\u0627\u0641\u0642 \u0645\u0639 \u0627\u0644\u062a\u0631\u0627\u062c\u0639 \u0627\u0644\u0646\u0627\u062c\u062d \u0648\u0627\u0644\u0645\u0633\u062a\u0645\u0631 \u0644\u0644\u0645\u0631\u0636.<\/p>\n

\u0623. \u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0626\u0648\u064a\u0629 \u0627\u0644\u0645\u0642\u062f\u0631\u0629 \u0644\u0627\u0646\u062d\u0633\u0627\u0631 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0627\u0644\u062a\u0627\u062c\u064a\u0629<\/h4>\n

\u064a\u0642\u062f\u0645 \u0627\u0644\u062c\u062f\u0648\u0644 \u0627\u0644\u062a\u0627\u0644\u064a \u0627\u0644\u062a\u063a\u064a\u0631 \u0627\u0644\u0645\u0626\u0648\u064a \u0627\u0644\u0645\u0642\u062f\u0631 \u0641\u064a \u0627\u0644\u0642\u0637\u0631 (\u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0626\u0648\u064a\u0629 \u0644\u062a\u0636\u064a\u0642 \u0627\u0644\u0642\u0637\u0631\u060c \u0623\u0648 %DS) \u0644\u0644\u0623\u062c\u0632\u0627\u0621 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629\u060c \u0627\u0644\u0645\u0633\u062a\u0645\u062f \u0645\u0646 \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0627\u0644\u0628\u0635\u0631\u064a\u0629 \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0627\u0641\u062a\u0631\u0627\u0636 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0646\u0647\u062c\u064a\u0629 QCA \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062f\u0642\u0629.<\/p>\n

\u0628. \u0627\u0644\u0627\u0633\u062a\u062f\u0644\u0627\u0644 \u0627\u0644\u0646\u0648\u0639\u064a \u0648\u0627\u0644\u0643\u0645\u064a \u0641\u064a \u0627\u0644\u0627\u0646\u062d\u062f\u0627\u0631 \u0645\u062a\u0639\u062f\u062f \u0627\u0644\u0628\u0624\u0631<\/h4>\n
    \n
  1. \u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u0641\u0631\u0639 \u0627\u0644\u0642\u0637\u0631\u064a:<\/strong> In 2014, the first diagonal branch origin (red circle) exhibited a high-grade, severe stenosis (estimated 60% \u00a0to \u00a075% \u00a0diameter reduction). In the 2018 follow-up, the segment is “\u0628\u0631\u0627\u0621\u0629 \u0627\u062e\u062a\u0631\u0627\u0639 \u0643\u0627\u0645\u0644\u0629<\/strong>,” indicating a reduction to likely less than \u00a010% \u00a0to \u00a020% \u00a0 This magnitude of reversal\u2014a change of up to \u00a065 \u00a0percentage points\u2014is consistent with the successful reversal of a highly vulnerable, lipid-rich atherosclerotic plaque.6<\/sup> Plaques rich in lipid and inflammatory content are highly responsive to intensive treatment, while calcified or dense fibrotic lesions are refractory to reversal.6<\/sup><\/li>\n
  2. \u062a\u0648\u0633\u064a\u0639 \u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u062a\u0627\u062c\u064a \u0627\u0644\u0623\u0645\u0627\u0645\u064a \u0627\u0644\u0646\u0627\u0632\u0644 (LAD) \u0648\u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u0645\u062d\u064a\u0637\u064a \u0628\u0634\u0643\u0644 \u0639\u0627\u0645:<\/strong> \u064a\u0634\u064a\u0631 \u0627\u0644\u062a\u0648\u0633\u0639 \u0627\u0644\u0645\u062a\u0633\u0642 \u0639\u0628\u0631 \u0627\u0644\u0645\u0642\u0627\u0637\u0639 \u0627\u0644\u0645\u0639\u064a\u0627\u0631\u064a\u0629 \u0644\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u062a\u0627\u062c\u064a \u0627\u0644\u0623\u064a\u0633\u0631 \u0627\u0644\u0623\u0645\u0627\u0645\u064a (LAD) \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u0645\u062d\u064a\u0637\u0629 \u0625\u0644\u0649 \u0627\u0646\u062e\u0641\u0627\u0636 \u0641\u064a \u0639\u0628\u0621 \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0627\u0644\u0645\u0646\u062a\u0634\u0631 \u0641\u064a \u062c\u0645\u064a\u0639 \u0623\u0646\u062d\u0627\u0621 \u062c\u062f\u0627\u0631 \u0627\u0644\u0634\u0631\u064a\u0627\u0646\u060c \u0648\u0647\u0648 \u0645\u0627 \u064a\u0645\u062b\u0644 positive arterial remodeling<\/strong>.8<\/sup> This generalized improvement rules out mechanical intervention (such as stenting or angioplasty), which would result in highly focal improvements, as the cause.1<\/sup> Furthermore, the lack of abnormal expansion rules out pathological dilation such as coronary artery ectasia.9<\/sup><\/li>\n<\/ol>\n

    \u0627\u0644\u0631\u0627\u0628\u0639: \u0627\u0644\u0641\u064a\u0632\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0645\u0631\u0636\u064a\u0629 \u0648\u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629<\/h3>\n

    The dramatic angiographic changes are the result of profound metabolic and structural shifts within the arterial wall, achieving a state of net atheroma volume removal.10<\/sup><\/p>\n

    \u0623. \u0627\u0644\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u0627\u0646\u062e\u0641\u0627\u0636 \u062d\u062c\u0645 \u0627\u0644\u0644\u0648\u064a\u062d\u0627\u062a \u0627\u0644\u062a\u0635\u0644\u0628\u064a\u0629<\/h4>\n

    Plaque regression is driven by specific biological healing mechanisms, primarily the net reduction in Percent Atheroma Volume (PAV).10<\/sup> The key mechanisms include increasing the capacity for cholesterol efflux from foam cells and clearing necrotic cell fragments contained within the plaque core, leading to physical plaque shrinkage.7<\/sup> \u062a\u062a\u0637\u0644\u0628 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0623\u0646 \u062a\u0635\u0644 \u0627\u0644\u0628\u064a\u0626\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0625\u0644\u0649 \u062d\u0627\u0644\u0629 \u064a\u062a\u0628\u0627\u0637\u0623 \u0641\u064a\u0647\u0627 \u0645\u0639\u062f\u0644 \u0625\u0632\u0627\u0644\u0629 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0645\u0646 \u062c\u062f\u0627\u0631 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0628\u0634\u0643\u0644 \u0645\u0644\u062d\u0648\u0638 \u064a\u062a\u0641\u0648\u0642 \u0639\u0644\u0649<\/em> the rate of deposition, creating a sustained net negative accumulation of plaque volume.11<\/sup><\/p>\n

    \u0628. \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629: \u0627\u0644\u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u0645\u0643\u062b\u0641 \u0644\u0646\u0645\u0637 \u0627\u0644\u062d\u064a\u0627\u0629<\/h4>\n

    \u064a\u064f\u0639\u062f \u062d\u062c\u0645 \u0648\u0646\u0645\u0637 \u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u2014 \u0623\u064a \u0627\u0644\u062a\u062d\u0633\u0646 \u0627\u0644\u0634\u0627\u0645\u0644 \u0641\u064a \u0639\u062f\u0629 \u0623\u0648\u0639\u064a\u0629 \u0645\u0639 \u0627\u0644\u0632\u0648\u0627\u0644 \u0627\u0644\u062a\u0627\u0645 \u0644\u0622\u0641\u0629 \u0634\u062f\u064a\u062f\u0629 \u0642\u062f \u062a\u0643\u0648\u0646 \u063a\u064a\u0631 \u0645\u0633\u062a\u0642\u0631\u0629 \u2014 \u0645\u0646 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0628\u0627\u0631\u0632\u0629 \u0644\u0644\u0623\u0633\u0627\u0644\u064a\u0628 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629. \u0648\u064a\u0631\u062a\u0628\u0637 \u0647\u0630\u0627 \u0627\u0644\u0645\u0633\u062a\u0648\u0649 \u0645\u0646 \u0627\u0644\u0634\u0641\u0627\u0621 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a \u0627\u0631\u062a\u0628\u0627\u0637\u064b\u0627 \u0648\u062b\u064a\u0642\u064b\u0627 \u0628\u062a\u0637\u0628\u064a\u0642 \u0627\u0644\u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u0645\u0643\u062b\u0641 \u0644\u0646\u0645\u0637 \u0627\u0644\u062d\u064a\u0627\u0629 (ILM)<\/strong> \u0627\u0644\u0628\u0631\u0627\u0645\u062c.10<\/sup><\/p>\n

    These programs, often modeled after the Ornish Lifestyle Medicine Program, demand rigor beyond conventional guidelines and typically include 10<\/sup>:<\/p>\n

      \n
    • A whole foods, plant-based diet very low in fat and sugar.11<\/sup><\/li>\n
    • \u0645\u0645\u0627\u0631\u0633\u0629 \u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u0631\u064a\u0627\u0636\u064a\u0629 \u0628\u0627\u0639\u062a\u062f\u0627\u0644 \u0648\u0628\u0634\u0643\u0644 \u0645\u0646\u062a\u0638\u0645.<\/li>\n
    • \u062a\u0642\u0646\u064a\u0627\u062a \u0645\u0646\u0638\u0645\u0629 \u0644\u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u062a\u0648\u062a\u0631 (\u0645\u062b\u0644 \u0627\u0644\u064a\u0648\u063a\u0627 \u0648\u0627\u0644\u062a\u0623\u0645\u0644).<\/li>\n
    • Enhanced social support to ensure long-term adherence.<\/li>\n<\/ul>\n

      \u0625\u0646 \u0645\u0644\u0627\u062d\u0638\u0629 \u062d\u062f\u0648\u062b \u062a\u0631\u0627\u062c\u0639 \u0645\u0633\u062a\u0645\u0631 \u0648\u0639\u0645\u064a\u0642 \u0639\u0644\u0649 \u0645\u062f\u0649 \u0627\u0644\u0641\u062a\u0631\u0629 \u0627\u0644\u0645\u0645\u062a\u062f\u0629 \u0644\u0623\u0631\u0628\u0639 \u0633\u0646\u0648\u0627\u062a \u0628\u064a\u0646 \u0639\u0627\u0645\u064a 2014 \u06482018 \u062a\u064f\u0639\u062f \u062f\u0644\u064a\u0644\u0627\u064b \u0645\u0648\u0636\u0648\u0639\u064a\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0627\u0644\u0645\u0633\u062a\u0645\u0631 \u0628\u0647\u0630\u0627 \u0627\u0644\u0646\u0638\u0627\u0645 \u0627\u0644\u0635\u0627\u0631\u0645 \u0648\u0627\u0644\u0645\u0643\u062b\u0641.10<\/sup><\/p>\n

      \u062e\u0627\u0645\u0633\u0627\u064b: \u0627\u0644\u062a\u0648\u0642\u0639\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/h3>\n

      Achieving angiographic regression translates directly into a reduction in the risk of future Major Adverse Cardiovascular Events (MACE).<\/p>\n

        \n
      • \u0627\u0644\u062d\u062f \u0645\u0646 \u0627\u0644\u0645\u062e\u0627\u0637\u0631:<\/strong> \u0623\u062b\u0628\u062a \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u0627\u0646\u062d\u062f\u0627\u0631 \u0627\u0644\u062a\u0644\u0648\u064a \u0623\u0646 \u0643\u0644 \u0627\u0646\u062e\u0641\u0627\u0636 \u0628\u0645\u0642\u062f\u0627\u0631 1% \u0641\u064a \u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0626\u0648\u064a\u0629 \u0644\u062d\u062c\u0645 \u0627\u0644\u0644\u0648\u064a\u062d\u0627\u062a (PAV) \u064a\u0631\u062a\u0628\u0637 \u0628\u0627\u0646\u062e\u0641\u0627\u0636 \u0628\u0645\u0642\u062f\u0627\u0631 20% \u0641\u064a \u0627\u062d\u062a\u0645\u0627\u0644\u0627\u062a \u062d\u062f\u0648\u062b \u0627\u0644\u0623\u062d\u062f\u0627\u062b \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u062e\u0637\u064a\u0631\u0629 (MACE).13<\/sup> \u0648\u0646\u0638\u0631\u0627\u064b \u0644\u0644\u062a\u062d\u0633\u0646 \u0627\u0644\u0628\u0635\u0631\u064a \u0627\u0644\u0643\u0628\u064a\u0631 \u0627\u0644\u0630\u064a \u0637\u0631\u0623 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0629\u060c \u0641\u0625\u0646 \u0627\u0644\u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0645\u0642\u062f\u0631 \u0641\u064a \u0645\u0624\u0634\u0631 PAV \u064a\u064f\u0639\u062f\u0651 \u0643\u0628\u064a\u0631\u0627\u064b\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u062a\u062d\u0648\u0644 \u0645\u0644\u062d\u0648\u0638 \u0645\u0646 \u0646\u0645\u0637 \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0639\u0627\u0644\u064a \u0627\u0644\u062e\u0637\u0648\u0631\u0629 (2014) \u0625\u0644\u0649 \u0646\u0645\u0637 \u0645\u0633\u062a\u0642\u0631 \u0648\u0645\u0646\u062e\u0641\u0636 \u0627\u0644\u062e\u0637\u0648\u0631\u0629 \u0644\u0644\u063a\u0627\u064a\u0629 (2018).13<\/sup><\/li>\n
      • Plaque Stabilization:<\/strong> \u064a\u0634\u064a\u0631 \u0647\u0630\u0627 \u0627\u0644\u062a\u0631\u0627\u062c\u0639 \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u0622\u0641\u0627\u062a \u0627\u0644\u063a\u0646\u064a\u0629 \u0628\u0627\u0644\u062f\u0647\u0648\u0646\u060c \u0627\u0644\u062a\u064a \u0643\u0627\u0646\u062a \u0641\u064a \u0627\u0644\u0633\u0627\u0628\u0642 \u063a\u064a\u0631 \u0645\u0633\u062a\u0642\u0631\u0629 \u0648\u0639\u0631\u0636\u0629 \u0644\u0644\u062a\u0645\u0632\u0642\u060c \u0642\u062f \u0627\u0633\u062a\u0642\u0631\u062a \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u064b\u0627 \u0648\u062a\u0642\u0644\u0635\u062a \u0647\u064a\u0643\u0644\u064a\u064b\u0651\u0627. \u0648\u064a\u064f\u0639\u062f \u0647\u0630\u0627 \u0627\u0644\u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0627\u0644\u0639\u0627\u0645\u0644 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0648\u0631\u0627\u0621 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0627\u0644\u062a\u0646\u0628\u0624\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644.6<\/sup><\/li>\n<\/ul>\n

        \u0627\u0644\u0645\u0631\u0627\u062c\u0639<\/h3>\n
          \n
        1. Ibanez B, Fern\u00e1ndez-Ortiz A, Fern\u00e1ndez-Friera L, Garc\u00eda-Lunar I, Andr\u00e9s V, Fuster V. Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7\/8.\u00a0\u0645\u062c\u0644\u0629 \u0627\u0644\u0643\u0644\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628<\/i>. 2021;78(2):156-179. doi:10.1016\/j.jacc.2021.05.011<\/li>\n
        2. Superko HR, Krauss RM. Coronary artery disease regression. Convincing evidence for the benefit of aggressive lipoprotein management.\u00a0\u0627\u0644\u062a\u062f\u0627\u0648\u0644<\/i>. 1994;90(2):1056-1069. doi:10.1161\/01.cir.90.2.1056<\/li>\n
        3. Garrone P, Biondi-Zoccai G, Salvetti I, et al. Quantitative coronary angiography in the current era: principles and applications.\u00a0J Interv Cardiol<\/i>. 2009;22(6):527-536. doi:10.1111\/j.1540-8183.2009.00491.x<\/li>\n
        4. Fencil LE, Doi K, Hoffman KR. Accurate analysis of blood vessel sizes and stenotic lesions using stereoscopic DSA system.\u00a0Invest Radiol<\/i>. 1988;23(1):33-41. doi:10.1097\/00004424-198801000-00008<\/li>\n
        5. Popma JJ, Lansky AJ, Yeh W, et al. Reliability of the quantitative angiographic measurements in the New Approaches to Coronary Intervention (NACI) registry: a comparison of clinical site and repeated angiographic core laboratory readings.\u00a0Am J Cardiol<\/i>. 1997;80(10A):19K-25K. doi:10.1016\/s0002-9149(97)00761-3<\/li>\n
        6. Lionakis N, Briasoulis A, Zouganeli V, et al. Coronary Artery Aneurysms: Comprehensive Review and a Case Report of a Left Main Coronary Artery Aneurysm.\u00a0Curr Probl Cardiol<\/i>. 2023;48(7):101700. doi:10.1016\/j.cpcardiol.2023.101700<\/li>\n
        7. Henzel J, K\u0119pka C, Kruk M, et al. High-Risk Coronary Plaque Regression After Intensive Lifestyle Intervention in Nonobstructive Coronary Disease: A Randomized Study.\u00a0\u0645\u062c\u0644\u0629 \u0627\u0644\u0643\u0644\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0623\u0628\u0631\u0632 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629<\/i>. 2021;14(6):1192-1202. doi:10.1016\/j.jcmg.2020.10.019<\/li>\n
        8. Barrett TJ. Macrophages in Atherosclerosis Regression.\u00a0Arterioscler Thromb Vasc Biol<\/i>. 2020;40(1):20-33. doi:10.1161\/ATVBAHA.119.312802<\/li>\n
        9. Ueki Y, Itagaki T, Kuwahara K. Lipid-lowering Therapy and Coronary Plaque Regression.\u00a0J Atheroscler Thromb<\/i>. 2024;31(11):1479-1495. doi:10.5551\/jat.RV22024<\/li>\n
        10. Ornish D, Scherwitz LW, Billings JH, et al. Intensive lifestyle changes for reversal of coronary heart disease.\u00a0\u062c\u0627\u0645\u0627<\/i>. 1998;280(23):2001-2007. doi:10.1001\/jama.280.23.2001<\/li>\n
        11. Gould KL, Ornish D, Scherwitz L, et al. Changes in myocardial perfusion abnormalities by positron emission tomography after long-term, intense risk factor modification.\u00a0\u062c\u0627\u0645\u0627<\/i>. 1995;274(11):894-901. doi:10.1001\/jama.1995.03530110056036<\/li>\n
        12. Shishikura D, Kataoka Y, Di Giovanni G, et al. Progression of ultrasound plaque attenuation and low echogenicity associates with major adverse cardiovascular events.\u00a0\u0645\u062c\u0644\u0629 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629<\/i>. 2020;41(31):2965-2973. doi:10.1093\/eurheartj\/ehaa173<\/li>\n
        13. \u00a0<\/span>Brieger D, Pocock SJ, Blankenberg S, et al. Two-year outcomes among stable high-risk patients following acute MI. Insights from a global registry in 25 countries.\u00a0Int J Cardiol<\/i>. 2020;311:7-14. doi:10.1016\/j.ijcard.2020.01.070<\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"

          \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0647\u0648 \u0645\u0631\u0636 \u0645\u0632\u0645\u0646 \u0648\u0645\u062a\u0641\u0627\u0642\u0645 \u064a\u0635\u064a\u0628 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0648\u064a\u064f\u0639\u0627\u0644\u062c \u0639\u0627\u062f\u0629\u064b \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u062f\u062e\u0644\u0627\u062a \u062a\u0647\u062f\u0641 \u0625\u0644\u0649 \u0625\u0628\u0637\u0627\u0621 \u062a\u0642\u062f\u0645\u0647.1 \u0648\u064a\u064f\u0639\u062f \u0627\u0644\u062a\u0631\u0627\u062c\u0639 \u0627\u0644\u0642\u0627\u0628\u0644 \u0644\u0644\u0642\u064a\u0627\u0633 \u0644\u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0629 \u2014 \u0627\u0644\u0630\u064a \u064a\u064f\u0639\u0631\u064e\u0651\u0641 \u0628\u0627\u0644\u062a\u0631\u0627\u062c\u0639 \u0627\u0644\u0647\u064a\u0643\u0644\u064a \u2014 \u0623\u0641\u0636\u0644 \u0646\u062a\u064a\u062c\u0629 \u0639\u0644\u0627\u062c\u064a\u0629 \u0641\u064a \u0625\u062f\u0627\u0631\u0629 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629.2 \u0648\u064a\u062a\u062c\u0644\u0649 \u0627\u0644\u062a\u0631\u0627\u062c\u0639 \u0641\u064a \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0627\u0644\u0648\u0639\u0627\u0626\u064a \u0645\u0646 \u062e\u0644\u0627\u0644 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0642\u0637\u0631 \u0627\u0644\u0623\u062f\u0646\u0649 \u0644\u0644\u0644\u0648\u0645\u064a\u0646 (MLD) \u0623\u0648 \u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0626\u0648\u064a\u0629 \u0644\u062a\u0636\u064a\u0642 \u0627\u0644\u0642\u0637\u0631 (%DS).<\/p>","protected":false},"author":16,"featured_media":8398,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[218,221,223,224],"tags":[],"class_list":["post-8395","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exercise-athletes-and-aging","category-peters-journey-and-records","category-plaque-arteries-and-disease","category-regression-and-reversal"],"acf":[],"yoast_head":"\nExpert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018) - 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