{"id":8435,"date":"2025-11-02T14:51:58","date_gmt":"2025-11-02T19:51:58","guid":{"rendered":"https:\/\/www.curingheartdisease.com\/?p=8435"},"modified":"2026-07-16T11:01:50","modified_gmt":"2026-07-16T15:01:50","slug":"%d8%a7%d9%84%d8%a7%d9%84%d8%aa%d9%87%d8%a7%d8%a8%d8%a7%d8%aa-%d9%88%d8%a7%d9%84%d8%a8%d8%b1%d9%88%d8%aa%d9%8a%d9%86%d8%a7%d8%aa-%d8%a7%d9%84%d8%af%d9%87%d9%86%d9%8a%d8%a9-%d9%88%d9%86%d9%87%d8%a7","status":"publish","type":"post","link":"https:\/\/www.curingheartdisease.com\/ar\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/","title":{"rendered":"\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u060c \u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u062f\u0647\u0646\u064a\u0629\u060c \u0648\u0646\u0647\u0627\u064a\u0629 \u0639\u0635\u0631 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0639\u0644\u0649 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0636\u0627\u0631"},"content":{"rendered":"

\"\"<\/p>\n

A Comprehensive Evaluation of Biomarkers in Cardiovascular Risk Stratification<\/h3>\n

I. Introduction: The Paradigm Shift<\/h3>\n

For decades, preventive cardiology has been anchored by a single, powerful concept: the “lipid hypothesis.” We operated under the assumption that cholesterol accumulation\u2014specifically LDL-C\u2014was the primary driver of atherosclerotic cardiovascular disease. The clinical directive was straightforward: push LDL-C down, and heart attack risk will follow. While this approach, largely driven by statin therapy, has undeniably saved millions of lives, we now know it is an incomplete strategy.<\/p>\n

Even when patients achieve aggressive LDL targets, a significant “residual risk” remains. We see this clinically every day: patients with “perfect” cholesterol levels who still suffer heart attacks. This persistence of risk has forced a re-evaluation of the disease model. We are moving away from viewing atherosclerosis as a passive “plumbing” problem\u2014pipes clogged by grease\u2014toward understanding it as immuno-lipidology<\/strong>. In this view, plaque is not just debris; it is a chronic, maladaptive inflammatory response to lipoprotein retention.<\/p>\n

Two major developments\u2014the 30-year follow-up of the Women\u2019s Health Study (published in the New England Journal of Medicine<\/em> in late 2024) [1] and the 2025 Scientific Statement from the American College of Cardiology [2]\u2014have fundamentally reshuffled our risk hierarchy. These reports suggest that High-Sensitivity C-Reactive Protein (hs-CRP), a marker of systemic inflammation, may actually outperform LDL-C in predicting long-term outcomes for many patients. At the same time, the reliance on LDL-C as a measure of particle burden is being rightly challenged by Apolipoprotein B (ApoB).<\/p>\n

This report analyzes this shift, moving beyond the headlines to the pathophysiology, and provides an evidence-based roadmap for managing this “triple threat” of risk: particle count, genetic susceptibility, and inflammation.<\/p>\n

II. The Mechanism: Why Inflammation Matters<\/h3>\n

To understand why a liver protein (CRP) might predict a heart attack better than cholesterol, we have to look at the vessel wall. The endothelium is not a passive lining; it is biologically active.<\/p>\n

2.1 Retention and Oxidation<\/strong><\/p>\n

The process starts with retention. Apolipoprotein B-containing particles (LDL, VLDL, Lp(a)) migrate into the sub-endothelial space. Crucially, they get stuck. Once trapped, these particles oxidize. The immune system does not recognize Oxidized LDL (OxLDL) as “self”; it perceives it as a pathogen, similar to a bacterium.<\/p>\n

2.2 The NLRP3 Inflammasome<\/strong><\/p>\n

This triggers the innate immune response. Macrophages rush in to engulf the oxidized lipids, becoming “foam cells.” This ingestion activates the NLRP3 inflammasome, a molecular complex that acts as a siren. It churns out Interleukin-1\u03b2 (IL-1\u03b2), which in turn stimulates Interleukin-6 (IL-6). When IL-6 reaches the liver, it triggers the production of C-Reactive Protein (CRP).<\/p>\n

Consequently, an elevated hs-CRP isn’t just a vague sign of “swelling.” It is a downstream readout of active plaque instability. Cholesterol builds the plaque, but inflammation is what weakens the cap, leading to rupture and thrombosis. This explains the data [3]: you can have a large, stable plaque (high cholesterol, low inflammation) that remains asymptomatic, or a smaller, inflamed plaque that ruptures and kills.<\/p>\n

III. The Biomarkers: A Modern Hierarchy<\/h3>\n

We need to evaluate the three key players in this landscape: hs-CRP, ApoB, and Lipoprotein(a).<\/p>\n

\"\"<\/h3>\n

3.1 High-Sensitivity C-Reactive Protein (hs-CRP)<\/strong><\/p>\n

Standard CRP tests detect acute infections. For cardiovascular risk, we need high-sensitivity assays that detect low-grade inflammation (typically 0.5 to 10 mg\/L).<\/p>\n

    \n
  • Low Risk:<\/strong> < 1.0 mg\/L<\/li>\n
  • High Risk:<\/strong> > 3.0 mg\/L<\/li>\n<\/ul>\n

    The 2024 Ridker study provided a sobering look at long-term risk. In nearly 28,000 women followed for 30 years, hs-CRP was a stronger predictor of future events than LDL-C [1]. The hazard ratio for the highest quintile of hs-CRP was 1.70<\/strong>, compared to 1.36<\/strong> for LDL-C. This suggests that for long-term prognosis, knowing a patient’s inflammatory status is non-negotiable.<\/p>\n

    This aligns with previous data from the JUPITER trial [5], which showed that rosuvastatin reduced events significantly in people with normal LDL but high hs-CRP. Notably, the greatest benefit was seen in those who achieved lower hs-CRP levels, suggesting a strong association between reducing inflammation and survival.<\/p>\n

    3.2 Apolipoprotein B (ApoB)<\/strong><\/p>\n

    LDL-C measures the mass of cholesterol, but the arterial wall cares about the number of particles. ApoB provides a 1:1 count of every atherogenic particle in circulation.<\/p>\n

    In patients with metabolic syndrome, obesity, or insulin resistance, we often see discordance<\/strong>: the LDL-C is normal, but the ApoB is sky-high because the cholesterol is carried in many small, dense particles. These small particles are more easily trapped in the arterial wall. This is why ApoB is a superior metric for estimating true lipoprotein burden [6, 7].<\/p>\n

    3.3 Lipoprotein(a) [Lp(a)]<\/strong><\/p>\n

    Lp(a) is often called the “genetic triple threat.” It is an LDL particle attached to an apo(a) tail. It promotes atherosclerosis (via cholesterol), inflammation (it carries oxidized phospholipids) [8], and thrombosis (it mimics plasminogen, inhibiting clot breakdown).<\/p>\n

    Unlike the other markers, Lp(a) is 80-90% genetic and barely moves with diet or exercise. It represents a fixed baseline risk. The new guidelines recommend every adult test this once to identify “hidden” risk that standard panels miss [2].<\/p>\n

    IV. Stratifying the “Triple Threat”<\/h3>\n

    The most important takeaway from the 2024\/2025 data is not that we should swap LDL for CRP, but that the risks are additive.<\/p>\n

    The Ridker data showed that while single elevations are bad, the combination is exponential [1].<\/p>\n

      \n
    • Single Marker Elevated:<\/strong> ~1.2x Risk<\/li>\n
    • All Three Elevated:<\/strong> ~2.6x Risk<\/li>\n<\/ul>\n

      The most dangerous patient is the one with high particle count (ApoB), high genetic susceptibility (Lp(a)), and active inflammation (hs-CRP).<\/p>\n

      V. From Theory to Therapy: Reducing Inflammatory Risk<\/h3>\n

      If hs-CRP is high (>2.0 mg\/L), “watch and wait” is no longer appropriate. We need a multimodal approach to cool the system.<\/p>\n

      5.1 Nutritional Immunology<\/strong><\/p>\n

      Diet is our primary lever. The Mediterranean diet remains the gold standard, not just for lipids, but for inflammation [9].<\/p>\n

        \n
      • Mechanism:<\/strong> It\u2019s not just about “healthy fats.” Extra virgin olive oil contains oleocanthal, a natural anti-inflammatory. High fiber intake feeds gut bacteria that produce butyrate, which strengthens the gut barrier and prevents bacterial toxins (LPS) from leaking into the bloodstream\u2014a major cause of systemic inflammation.<\/li>\n
      • Glycemic Control:<\/strong> Insulin resistance is a pro-inflammatory state. Minimizing glucose spikes and eliminating ultra-processed foods (which often contain gut-disrupting emulsifiers) is critical [10].<\/li>\n<\/ul>\n

        5.2 The Exercise “Vaccine”<\/strong><\/p>\n

        Exercise offers a paradox: acute, heavy exertion can temporarily raise inflammatory markers, but chronic training lowers them [11]. Skeletal muscle acts as an endocrine organ. When muscles contract, they release myokines (muscle-derived IL-6) that paradoxically act as anti-inflammatory signals, blocking the pathways that lead to chronic inflammation.<\/p>\n

        5.3 Lifestyle Hygiene<\/strong><\/p>\n

          \n
        • Oral Health:<\/strong> Periodontitis is a vascular threat. It creates a chronic bacterial load that enters the bloodstream. Treating gum disease has been shown to lower systemic CRP [12].<\/li>\n
        • Sleep:<\/strong> Both sleep deprivation and sleep apnea drive inflammation via oxidative stress. Correcting apnea (CPAP) and ensuring 7-8 hours of sleep are fundamental anti-inflammatory interventions [13, 14].<\/li>\n<\/ul>\n

          5.4 Pharmacotherapy<\/strong><\/p>\n

          When lifestyle isn’t enough, we have tools:<\/p>\n

            \n
          • Statins:<\/strong> They are dual inhibitors. They lower cholesterol, but they also dampen the inflammatory response in the vessel wall [4].<\/li>\n
          • Colchicine:<\/strong> This is the game-changer for residual inflammatory risk. The COLCOT [15] and LoDoCo2 [16] trials showed that low-dose colchicine (0.5mg) significantly reduced cardiovascular events. It works by blocking the assembly of the NLRP3 inflammasome, stopping inflammation at the source.<\/li>\n
          • The Future:<\/strong> Drugs like Ziltivekimab (an IL-6 inhibitor) are currently in trials for patients with chronic kidney disease and high CRP, offering hope for even more targeted therapy.<\/li>\n<\/ul>\n

            VI. Conclusion<\/h3>\n

            The debate is settled: Inflammation is a mechanism of disease, not just a bystander. The data clearly shows that hs-CRP belongs alongside ApoB and Lp(a) in a modern risk assessment.<\/p>\n

            We must move beyond the “plumbing” model. The goal of therapy is no longer just to lower a number on a lipid panel; it is to stabilize the biology of the artery. This requires a comprehensive strategy that lowers the particle burden to physiological levels while simultaneously extinguishing the inflammatory fire.<\/p>\n

            \"\"References<\/h3>\n
              \n
            1. Ridker PM, Moorthy MV, Cook NR, Rifai N, Lee IM, Buring JE. Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women.\u00a0N Engl J Med<\/i>. 2024;391(22):2087-2097. doi:10.1056\/NEJMoa2405182<\/li>\n
            2. Mensah GA, Arnold N, Prabhu SD, Ridker PM, Welty FK. Inflammation and Cardiovascular Disease: 2025 ACC Scientific Statement: A Report of the American College of Cardiology.\u00a0J Am Coll Cardiol<\/i>. Published online September 29, 2025. doi:10.1016\/j.jacc.2025.08.047<\/li>\n
            3. Libby P. The changing landscape of atherosclerosis.\u00a0Nature<\/i>. 2021;592(7855):524-533. doi:10.1038\/s41586-021-03392-8<\/li>\n
            4. Ridker PM, Cannon CP, Morrow D, et al. C-reactive protein levels and outcomes after statin therapy.\u00a0N Engl J Med<\/i>. 2005;352(1):20-28. doi:10.1056\/NEJMoa042378<\/li>\n
            5. Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.\u00a0N Engl J Med<\/i>. 2008;359(21):2195-2207. doi:10.1056\/NEJMoa0807646<\/li>\n
            6. Sniderman AD, Williams K, Contois JH, et al. A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk.\u00a0Circ Cardiovasc Qual Outcomes<\/i>. 2011;4(3):337-345. doi:10.1161\/CIRCOUTCOMES.110.959247<\/li>\n
            7. McQueen MJ, Hawken S, Wang X, et al. Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study.\u00a0Lancet<\/i>. 2008;372(9634):224-233. doi:10.1016\/S0140-6736(08)61076-4<\/li>\n
            8. Tsimikas S. A Test in Context: Lipoprotein(a): Diagnosis, Prognosis, Controversies, and Emerging Therapies.\u00a0J Am Coll Cardiol<\/i>. 2017;69(6):692-711. doi:10.1016\/j.jacc.2016.11.042<\/li>\n
            9. Estruch R, Ros E, Salas-Salvad\u00f3 J, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts.\u00a0N Engl J Med<\/i>. 2018;378(25):e34. doi:10.1056\/NEJMoa1800389<\/li>\n
            10. Sacks FM, Bray GA, Carey VJ, et al. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates.\u00a0N Engl J Med<\/i>. 2009;360(9):859-873. doi:10.1056\/NEJMoa0804748<\/li>\n
            11. Fedewa MV, Hathaway ED, Ward-Ritacco CL. Effect of exercise training on C reactive protein: a systematic review and meta-analysis of randomised and non-randomised controlled trials.\u00a0Br J Sports Med<\/i>. 2017;51(8):670-676. doi:10.1136\/bjsports-2016-095999<\/li>\n
            12. Demmer RT, Trinquart L, Zuk A, et al. The influence of anti-infective periodontal treatment on C-reactive protein: a systematic review and meta-analysis of randomized controlled trials.\u00a0PLoS One<\/i>. 2013;8(10):e77441. Published 2013 Oct 14. doi:10.1371\/journal.pone.0077441<\/li>\n
            13. Meier-Ewert HK, Ridker PM, Rifai N, et al. Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk.\u00a0J Am Coll Cardiol<\/i>. 2004;43(4):678-683. doi:10.1016\/j.jacc.2003.07.050<\/li>\n
            14. Guo Y, Pan L, Ren D, Xie X. Impact of continuous positive airway pressure on C-reactive protein in patients with obstructive sleep apnea: a meta-analysis.\u00a0Sleep Breath<\/i>. 2013;17(2):495-503. doi:10.1007\/s11325-012-0722-2<\/li>\n
            15. Tardif JC, Kouz S, Waters DD, et al. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.\u00a0N Engl J Med<\/i>. 2019;381(26):2497-2505. doi:10.1056\/NEJMoa1912388<\/li>\n
            16. \u00a0<\/span>Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in Patients with Chronic Coronary Disease.\u00a0N Engl J Med<\/i>. 2020;383(19):1838-1847. doi:10.1056\/NEJMoa2021372<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

              \u0644\u0639\u0642\u0648\u062f \u0645\u0646 \u0627\u0644\u0632\u0645\u0646\u060c \u0627\u0631\u062a\u0643\u0632\u062a \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0648\u0642\u0627\u0626\u064a\u0629 \u0639\u0644\u0649 \u0645\u0641\u0647\u0648\u0645 \u0648\u0627\u062d\u062f \u0642\u0648\u064a: \u201c\u0641\u0631\u0636\u064a\u0629 \u0627\u0644\u062f\u0647\u0648\u0646\u201d. \u0644\u0642\u062f \u0639\u0645\u0644\u0646\u0627 \u062a\u062d\u062a \u0627\u0641\u062a\u0631\u0627\u0636 \u0623\u0646 \u062a\u0631\u0627\u0643\u0645 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 - \u0648\u062a\u062d\u062f\u064a\u062f\u0627\u064b \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0636\u0627\u0631 (LDL-C) - \u0643\u0627\u0646 \u0627\u0644\u0645\u062d\u0631\u0643 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u062a\u0635\u0644\u0628 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646. \u0648\u0643\u0627\u0646\u062a \u0627\u0644\u062a\u0648\u062c\u064a\u0647\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0636\u062d\u0629 \u0648\u0645\u0628\u0627\u0634\u0631\u0629: \u062e\u0641\u0636 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0636\u0627\u0631\u060c \u0648\u0633\u064a\u062d\u0630\u0648 \u062d\u0630\u0648\u0647 \u0627\u0646\u062e\u0641\u0627\u0636 \u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0646\u0648\u0628\u0627\u062a \u0627\u0644\u0642\u0644\u0628\u064a\u0629. \u0648\u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0647\u0630\u0627 \u0627\u0644\u0646\u0647\u062c\u060c \u0627\u0644\u0645\u062f\u0641\u0648\u0639 \u0625\u0644\u0649 \u062d\u062f \u0643\u0628\u064a\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u0633\u062a\u0627\u062a\u064a\u0646\u060c \u0642\u062f \u0623\u0646\u0642\u0630 \u0645\u0644\u0627\u064a\u064a\u0646 \u0627\u0644\u0623\u0631\u0648\u0627\u062d \u0628\u0634\u0643\u0644 \u0644\u0627 \u064a\u062c\u0647\u062f\u060c \u0641\u0625\u0646\u0646\u0627 \u0646\u0639\u0644\u0645 \u0627\u0644\u0622\u0646 \u0623\u0646\u0647 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u063a\u064a\u0631 \u0645\u0643\u062a\u0645\u0644\u0629.<\/p>","protected":false},"author":16,"featured_media":8437,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[252,219,232,223],"tags":[],"class_list":["post-8435","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-inflammation-markers","category-lipids-medications-and-testing","category-plaque-biology","category-plaque-arteries-and-disease"],"acf":[],"yoast_head":"\nInflammation, Lipoproteins, and the End of the LDL-Centric Era - The Premiere Heart Health Education Platform<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.curingheartdisease.com\/ar\/\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a-\u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a-\u0627\u0644\u062f\u0647\u0646\u064a\u0629-\u0648\u0646\u0647\u0627\/\" \/>\n<meta property=\"og:locale\" content=\"ar_AR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inflammation, Lipoproteins, and the End of the LDL-Centric Era - The Premiere Heart Health Education Platform\" \/>\n<meta property=\"og:description\" content=\"For decades, preventive cardiology has been anchored by a single, powerful concept: the "lipid hypothesis." We operated under the assumption that cholesterol accumulation\u2014specifically LDL-C\u2014was the primary driver of atherosclerotic cardiovascular disease. The clinical directive was straightforward: push LDL-C down, and heart attack risk will follow. While this approach, largely driven by statin therapy, has undeniably saved millions of lives, we now know it is an incomplete strategy.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.curingheartdisease.com\/ar\/\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a-\u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a-\u0627\u0644\u062f\u0647\u0646\u064a\u0629-\u0648\u0646\u0647\u0627\/\" \/>\n<meta property=\"og:site_name\" content=\"The Premiere Heart Health Education Platform\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/curingheartdisease\" \/>\n<meta property=\"article:published_time\" content=\"2025-11-02T19:51:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-16T15:01:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-17.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Peter Megdal PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@RMHDInc\" \/>\n<meta name=\"twitter:site\" content=\"@RMHDInc\" \/>\n<meta name=\"twitter:label1\" content=\"\u0643\u064f\u062a\u0628 \u0628\u0648\u0627\u0633\u0637\u0629\" \/>\n\t<meta name=\"twitter:data1\" content=\"Peter Megdal PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u0648\u0642\u062a \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0645\u064f\u0642\u062f\u0651\u0631\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 \u062f\u0642\u0627\u0626\u0642\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/\"},\"author\":{\"name\":\"Peter Megdal PhD\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\"},\"headline\":\"Inflammation, Lipoproteins, and the End of the LDL-Centric Era\",\"datePublished\":\"2025-11-02T19:51:58+00:00\",\"dateModified\":\"2026-07-16T15:01:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/\"},\"wordCount\":1743,\"publisher\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-17.jpg\",\"articleSection\":[\"Inflammation Markers\",\"Lipids, Medications and Testing\",\"Plaque Biology\",\"Plaque, Arteries and Disease\"],\"inLanguage\":\"ar\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/\",\"name\":\"Inflammation, Lipoproteins, and the End of the LDL-Centric Era - The Premiere Heart Health Education Platform\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-17.jpg\",\"datePublished\":\"2025-11-02T19:51:58+00:00\",\"dateModified\":\"2026-07-16T15:01:50+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#breadcrumb\"},\"inLanguage\":\"ar\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ar\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-17.jpg\",\"contentUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-17.jpg\",\"width\":1200,\"height\":630},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.curingheartdisease.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Inflammation, Lipoproteins, and the End of the LDL-Centric Era\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#website\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/\",\"name\":\"The Premiere Heart Health Education Platform\",\"description\":\"To make available to the public the state of the art information on how to reverse heart disease. This is an evidence-based organization utilizing the best available science, including diet, exercise drugs, and other resources to best fight this disease.\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.curingheartdisease.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ar\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\",\"name\":\"Curing Heart Disease, LLC\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ar\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/cropped-Curing-Heart-icon-red.png\",\"contentUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/cropped-Curing-Heart-icon-red.png\",\"width\":512,\"height\":512,\"caption\":\"Curing Heart Disease, LLC\"},\"image\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/curingheartdisease\",\"https:\\\/\\\/x.com\\\/RMHDInc\",\"https:\\\/\\\/www.instagram.com\\\/rmhdinc\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCm8dh9c_D5RfJL7Z1f-yY4w\"],\"description\":\"Curing Heart Disease, LLC is an independent cardiovascular health education organization that publishes evidence-based articles, videos, podcasts, and educational tools about cardiovascular disease prevention, lipid science, nutrition, exercise, and related health topics.\",\"founder\":{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\",\"name\":\"Peter Megdal, PhD\"},\"foundingPerson\":{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\",\"name\":\"Peter Megdal, PhD\"},\"knowsAbout\":[\"Cardiovascular health\",\"Cardiovascular disease prevention\",\"Heart disease education\",\"Nutrition\",\"Exercise\",\"Lipid science\",\"Atherosclerosis\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\",\"name\":\"Peter Megdal, PhD\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/peters-story\\\/\",\"givenName\":\"Peter\",\"familyName\":\"Megdal\",\"honorificSuffix\":\"PhD\",\"jobTitle\":\"Nutrition Researcher and Cardiovascular Health Educator\",\"description\":\"Peter Megdal, PhD, is a nutrition researcher, cardiovascular health educator, published researcher, and longtime competitive cyclist. He earned a PhD in nutrition from the University of Massachusetts and publishes evidence-based cardiovascular health education through Curing Heart Disease.\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/peters-story\\\/\"},\"worksFor\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"affiliation\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"alumniOf\":{\"@type\":\"CollegeOrUniversity\",\"name\":\"University of Massachusetts\"},\"knowsAbout\":[\"Nutrition\",\"Cardiovascular health education\",\"Cardiovascular disease prevention\",\"Lipid science\",\"Exercise physiology\",\"Scientific research\"],\"sameAs\":[\"https:\\\/\\\/www.curingheartdisease.com\\\/author\\\/peter-megdal\\\/\",\"https:\\\/\\\/www.linkedin.com\\\/in\\\/peter-megdal-56075a2\\\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u060c \u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u062f\u0647\u0646\u064a\u0629\u060c \u0648\u0646\u0647\u0627\u064a\u0640\u0629 \u0639\u0647\u062f \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0639\u0644\u0649 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0636\u0627\u0631 (LDL) - \u0627\u0644\u0645\u0646\u0635\u0629 \u0627\u0644\u0631\u0627\u0626\u062f\u0629 \u0644\u062a\u062b\u0642\u064a\u0641 \u0635\u062d\u0629 \u0627\u0644\u0642\u0644\u0628","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.curingheartdisease.com\/ar\/\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a-\u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a-\u0627\u0644\u062f\u0647\u0646\u064a\u0629-\u0648\u0646\u0647\u0627\/","og_locale":"ar_AR","og_type":"article","og_title":"Inflammation, Lipoproteins, and the End of the LDL-Centric Era - The Premiere Heart Health Education Platform","og_description":"For decades, preventive cardiology has been anchored by a single, powerful concept: the \"lipid hypothesis.\" We operated under the assumption that cholesterol accumulation\u2014specifically LDL-C\u2014was the primary driver of atherosclerotic cardiovascular disease. The clinical directive was straightforward: push LDL-C down, and heart attack risk will follow. While this approach, largely driven by statin therapy, has undeniably saved millions of lives, we now know it is an incomplete strategy.","og_url":"https:\/\/www.curingheartdisease.com\/ar\/\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a-\u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a-\u0627\u0644\u062f\u0647\u0646\u064a\u0629-\u0648\u0646\u0647\u0627\/","og_site_name":"The Premiere Heart Health Education Platform","article_publisher":"https:\/\/www.facebook.com\/curingheartdisease","article_published_time":"2025-11-02T19:51:58+00:00","article_modified_time":"2026-07-16T15:01:50+00:00","og_image":[{"width":1200,"height":630,"url":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-17.jpg","type":"image\/jpeg"}],"author":"Peter Megdal PhD","twitter_card":"summary_large_image","twitter_creator":"@RMHDInc","twitter_site":"@RMHDInc","twitter_misc":{"\u0643\u064f\u062a\u0628 \u0628\u0648\u0627\u0633\u0637\u0629":"Peter Megdal PhD","\u0648\u0642\u062a \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0645\u064f\u0642\u062f\u0651\u0631":"9 \u062f\u0642\u0627\u0626\u0642"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#article","isPartOf":{"@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/"},"author":{"name":"Peter Megdal PhD","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53"},"headline":"Inflammation, Lipoproteins, and the End of the LDL-Centric Era","datePublished":"2025-11-02T19:51:58+00:00","dateModified":"2026-07-16T15:01:50+00:00","mainEntityOfPage":{"@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/"},"wordCount":1743,"publisher":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"image":{"@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#primaryimage"},"thumbnailUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-17.jpg","articleSection":["Inflammation Markers","Lipids, Medications and Testing","Plaque Biology","Plaque, Arteries and Disease"],"inLanguage":"ar"},{"@type":"WebPage","@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/","url":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/","name":"\u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u060c \u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u062f\u0647\u0646\u064a\u0629\u060c \u0648\u0646\u0647\u0627\u064a\u0640\u0629 \u0639\u0647\u062f \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0639\u0644\u0649 \u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644 \u0627\u0644\u0636\u0627\u0631 (LDL) - \u0627\u0644\u0645\u0646\u0635\u0629 \u0627\u0644\u0631\u0627\u0626\u062f\u0629 \u0644\u062a\u062b\u0642\u064a\u0641 \u0635\u062d\u0629 \u0627\u0644\u0642\u0644\u0628","isPartOf":{"@id":"https:\/\/www.curingheartdisease.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#primaryimage"},"image":{"@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#primaryimage"},"thumbnailUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-17.jpg","datePublished":"2025-11-02T19:51:58+00:00","dateModified":"2026-07-16T15:01:50+00:00","breadcrumb":{"@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#breadcrumb"},"inLanguage":"ar","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/"]}]},{"@type":"ImageObject","inLanguage":"ar","@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#primaryimage","url":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-17.jpg","contentUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-17.jpg","width":1200,"height":630},{"@type":"BreadcrumbList","@id":"https:\/\/www.curingheartdisease.com\/inflammation-lipoproteins-and-the-end-of-the-ldl-centric-era\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.curingheartdisease.com\/"},{"@type":"ListItem","position":2,"name":"Inflammation, Lipoproteins, and the End of the LDL-Centric Era"}]},{"@type":"WebSite","@id":"https:\/\/www.curingheartdisease.com\/#website","url":"https:\/\/www.curingheartdisease.com\/","name":"\u0645\u0646\u0635\u0629 \u0627\u0644\u062a\u062b\u0642\u064a\u0641 \u0627\u0644\u0635\u062d\u064a \u0644\u0644\u0642\u0644\u0628 \u0627\u0644\u0631\u0627\u0626\u062f\u0629","description":"\u0625\u062a\u0627\u062d\u0629 \u0623\u062d\u062f\u062b \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0644\u0644\u062c\u0645\u0647\u0648\u0631 \u062d\u0648\u0644 \u0643\u064a\u0641\u064a\u0629 \u0639\u0643\u0633 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628. \u0647\u0630\u0647 \u0645\u0646\u0638\u0645\u0629 \u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u0623\u062f\u0644\u0629 \u0648\u062a\u0633\u062a\u062e\u062f\u0645 \u0623\u0641\u0636\u0644 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0645\u062a\u0627\u062d\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0646\u0638\u0627\u0645 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u060c \u0648\u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u0631\u064a\u0627\u0636\u064a\u0629\u060c \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629\u060c \u0648\u063a\u064a\u0631\u0647\u0627 \u0645\u0646 \u0627\u0644\u0645\u0648\u0627\u0631\u062f \u0644\u0645\u062d\u0627\u0631\u0628\u0629 \u0647\u0630\u0627 \u0627\u0644\u0645\u0631\u0636 \u0628\u0623\u0641\u0636\u0644 \u0634\u0643\u0644 \u0645\u0645\u0643\u0646.","publisher":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.curingheartdisease.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ar"},{"@type":"Organization","@id":"https:\/\/www.curingheartdisease.com\/#organization","name":"\u0634\u0631\u0643\u0629 \u0639\u0644\u0627\u062c \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0645\u062d\u062f\u0648\u062f\u0629","url":"https:\/\/www.curingheartdisease.com\/","logo":{"@type":"ImageObject","inLanguage":"ar","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/logo\/image\/","url":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2026\/06\/cropped-Curing-Heart-icon-red.png","contentUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2026\/06\/cropped-Curing-Heart-icon-red.png","width":512,"height":512,"caption":"Curing Heart Disease, LLC"},"image":{"@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/curingheartdisease","https:\/\/x.com\/RMHDInc","https:\/\/www.instagram.com\/rmhdinc\/","https:\/\/www.youtube.com\/channel\/UCm8dh9c_D5RfJL7Z1f-yY4w"],"description":"\u0634\u0631\u0643\u0629 \u0639\u0644\u0627\u062c \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0645\u062d\u062f\u0648\u062f\u0629 (Curing Heart Disease, LLC) \u0647\u064a \u0645\u0646\u0638\u0645\u0629 \u0645\u0633\u062a\u0642\u0644\u0629 \u0644\u0644\u062a\u062b\u0642\u064a\u0641 \u0627\u0644\u0635\u062d\u064a \u0644\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u062a\u0646\u0634\u0631 \u0645\u0642\u0627\u0644\u0627\u062a \u0648\u0645\u0642\u0627\u0637\u0639 \u0641\u064a\u062f\u064a\u0648 \u0648\u0628\u0648\u062f\u06a9\u0627\u062a \u0648\u0623\u062f\u0648\u0627\u062a \u062a\u0639\u0644\u064a\u0645\u064a\u0629 \u0645\u062f\u0639\u0648\u0645\u0629 \u0628\u0627\u0644\u0623\u062f\u0644\u0629 \u062d\u0648\u0644 \u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0648\u0639\u0644\u0645 \u0627\u0644\u062f\u0647\u0648\u0646\u060c \u0648\u0627\u0644\u062a\u063a\u0630\u064a\u0629\u060c \u0648\u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u0631\u064a\u0627\u0636\u064a\u0629\u060c \u0648\u0627\u0644\u0645\u0648\u0627\u0636\u064a\u0639 \u0627\u0644\u0635\u062d\u064a\u0629 \u0630\u0627\u062a \u0627\u0644\u0635\u0644\u0629.","founder":{"@type":"Person","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53","name":"Peter Megdal, PhD"},"foundingPerson":{"@type":"Person","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53","name":"Peter Megdal, PhD"},"knowsAbout":["Cardiovascular health","Cardiovascular disease prevention","Heart disease education","Nutrition","Exercise","Lipid science","Atherosclerosis"]},{"@type":"Person","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53","name":"Peter Megdal, PhD","url":"https:\/\/www.curingheartdisease.com\/peters-story\/","givenName":"Peter","familyName":"Megdal","honorificSuffix":"PhD","jobTitle":"Nutrition Researcher and Cardiovascular Health Educator","description":"Peter Megdal, PhD\u060c \u0647\u0648 \u0628\u0627\u062d\u062b \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u062a\u063a\u0630\u064a\u0629\u060c \u0648\u0645\u062b\u0642\u0641 \u0641\u064a \u0645\u062c\u0627\u0644 \u0635\u062d\u0629 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0648\u0628\u0627\u062d\u062b \u0644\u0647 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0646\u0634\u0648\u0631\u0627\u062a \u0627\u0644\u0639\u0644\u0645\u064a\u0629\u060c \u0648\u062f\u0631\u0627\u062c \u062a\u0646\u0627\u0641\u0633\u064a \u0645\u0646\u0630 \u0641\u062a\u0631\u0629 \u0637\u0648\u064a\u0644\u0629. \u062d\u0635\u0644 \u0639\u0644\u0649 \u062f\u0631\u062c\u0629 \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u0641\u064a \u0627\u0644\u062a\u063a\u0630\u064a\u0629 \u0645\u0646 \u062c\u0627\u0645\u0639\u0629 \u0645\u0627\u0633\u0627\u062a\u0634\u0648\u0633\u062a\u0633\u060c \u0648\u064a\u0642\u0648\u0645 \u0628\u0646\u0634\u0631 \u0645\u0648\u0627\u062f \u062a\u062b\u0642\u064a\u0641\u064a\u0629 \u062d\u0648\u0644 \u0635\u062d\u0629 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u062a\u0633\u062a\u0646\u062f \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0645\u0648\u0642\u0639 \u00abCuring Heart Disease\u00bb.","mainEntityOfPage":{"@id":"https:\/\/www.curingheartdisease.com\/peters-story\/"},"worksFor":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"affiliation":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"alumniOf":{"@type":"CollegeOrUniversity","name":"University of Massachusetts"},"knowsAbout":["Nutrition","Cardiovascular health education","Cardiovascular disease prevention","Lipid science","Exercise physiology","Scientific research"],"sameAs":["https:\/\/www.curingheartdisease.com\/author\/peter-megdal\/","https:\/\/www.linkedin.com\/in\/peter-megdal-56075a2\/"]}]}},"_links":{"self":[{"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/posts\/8435","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/comments?post=8435"}],"version-history":[{"count":16,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/posts\/8435\/revisions"}],"predecessor-version":[{"id":12121,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/posts\/8435\/revisions\/12121"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/media\/8437"}],"wp:attachment":[{"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/media?parent=8435"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/categories?post=8435"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/ar\/wp-json\/wp\/v2\/tags?post=8435"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}