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Koronare Atherosklerose kann sich unter definierten Bedingungen zur\u00fcckbilden. Serielle intravaskul\u00e4re Ultraschalluntersuchungen (IVUS) und koronare Computertomographie-Angiographien (CCTA) zeigen, dass eine intensive Senkung des LDL-Cholesterins (LDL-C) durch hochdosierte Statine, PCSK9-Hemmer und, in ausgew\u00e4hlten F\u00e4llen, Icosapent-Ethyl das Plaquevolumen verringern kann. Paradoxerweise bleibt das arterielle Lumen oft unver\u00e4ndert oder kann sich sogar durch ein inverses oder konstriktives Remodeling verengen. 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