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La aterosclerosis coronaria puede regresar bajo condiciones definidas. Los estudios seriados de ecograf\u00eda intravascular (IVUS) y de angiograf\u00eda por tomograf\u00eda computarizada coronaria (CCTA) muestran que la reducci\u00f3n intensiva del colesterol de lipoprote\u00ednas de baja densidad (LDL-C) mediante estatinas de alta intensidad, inhibidores de PCSK9 y, en entornos seleccionados, icosapento de etilo, puede reducir el volumen de la placa. Parad\u00f3jicamente, la luz arterial a menudo permanece sin cambios o puede incluso estrecharse debido al remodelado inverso o constrictivo. 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