{"id":8395,"date":"2025-07-26T10:48:33","date_gmt":"2025-07-26T14:48:33","guid":{"rendered":"https:\/\/www.curingheartdisease.com\/?p=8395"},"modified":"2026-07-16T11:04:38","modified_gmt":"2026-07-16T15:04:38","slug":"evaluation-angiographique-specialisee-de-la-regression-de-la-coronaropathie-serie-dangiographies-megdal-2014-2018","status":"publish","type":"post","link":"https:\/\/www.curingheartdisease.com\/fr\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/","title":{"rendered":"\u00c9valuation angiographique experte de la r\u00e9gression de la maladie coronarienne : l'angiogramme s\u00e9riel Megdal (2014-2018)"},"content":{"rendered":"

I. Introduction : contextualisation de la r\u00e9gression de la maladie coronarienne<\/h3>\n

\"\"L'ath\u00e9roscl\u00e9rose est une affection vasculaire chronique et \u00e9volutive, traditionnellement prise en charge par des interventions visant \u00e0 en ralentir la progression.1<\/sup> La r\u00e9versibilit\u00e9 mesurable de cette affection, d\u00e9finie comme une r\u00e9gression structurelle, constitue le r\u00e9sultat th\u00e9rapeutique ultime dans la prise en charge des maladies cardiovasculaires.2<\/sup> La r\u00e9gression est mise en \u00e9vidence par angiographie par une augmentation du diam\u00e8tre minimal de la lumi\u00e8re (MLD) ou une diminution du pourcentage de st\u00e9nose (%DS).2<\/sup> Les essais cliniques utilisant l'art\u00e9riographie coronaire s\u00e9ri\u00e9e ont constamment d\u00e9montr\u00e9 qu'une modification agressive des facteurs de risque peut entra\u00eener des am\u00e9liorations significatives des mesures art\u00e9riographiques dans un laps de temps relativement court, s'\u00e9tendant souvent de deux \u00e0 quatre ans.2<\/sup><\/p>\n

L'angioscanner coronaire s\u00e9quentiel compare l'anatomie coronaire du patient en 2014 et 2018, englobant un intervalle critique de quatre ans. Fait crucial, les images ont \u00e9t\u00e9 acquises sur la \u201c m\u00eame machine \u201d et ont \u00e9t\u00e9 \u201c \u00e9talonn\u00e9es en fonction de la taille du calibre \u201d, \u00e9tablissant une m\u00e9thodologie robuste de qualit\u00e9 recherche pour la comparaison. Le changement visuel qui en r\u00e9sulte est spectaculaire : un \u00e9largissement g\u00e9n\u00e9ralis\u00e9 des vaisseaux de toutes les grandes art\u00e8res \u00e9picardiques (l'art\u00e8re interventriculaire ant\u00e9rieure et la circonflexe) et, plus remarquablement, la r\u00e9solution compl\u00e8te d'une st\u00e9nose serr\u00e9e et localis\u00e9e \u00e0 l'origine d'une branche diagonale, qui a atteint un \u00e9tat \u201c totalement perm\u00e9able \u201d en 2018.<\/p>\n

II. Fondement m\u00e9thodologique : Int\u00e9grit\u00e9 de l'angiographie coronaire quantitative<\/h3>\n

L'int\u00e9grit\u00e9 de la comparaison de deux \u00e9tudes angiographiques s\u00e9par\u00e9es par quatre ans repose sur un contr\u00f4le m\u00e9thodologique rigoureux. La confirmation de l'utilisateur que les \u00e9tudes ont \u00e9t\u00e9 r\u00e9alis\u00e9es dans le \u201c m\u00eame h\u00f4pital sur la m\u00eame machine \u201d et ont \u00e9t\u00e9 \u201c calibr\u00e9es pour la taille du calibre \u201d valide l'\u00e9valuation en tant qu'analyse quantitative de haute fid\u00e9lit\u00e9.<\/p>\n

A. Principes et validation de l'AQCS dans les \u00e9tudes s\u00e9rielles<\/h4>\n

La m\u00e9thode standard pour la mesure objective des dimensions luminales coronaires est l'angiographie coronaire quantitative (QCA).3<\/sup> Pour garantir l'exactitude, la QCA n\u00e9cessite une \u00e9tape de calibration pour convertir les mesures en pixels en v\u00e9ritables unit\u00e9s physiques (millim\u00e8tres).4<\/sup> L'utilisation du m\u00eame syst\u00e8me d'imagerie minimise les erreurs li\u00e9es \u00e0 la g\u00e9om\u00e9trie du d\u00e9tecteur et aux algorithmes de traitement d'image.4<\/sup> De plus, la confirmation que le syst\u00e8me a \u00e9t\u00e9 explicitement \u201c calibr\u00e9 \u201d signifie que des facteurs de correction g\u00e9om\u00e9trique coh\u00e9rents ont \u00e9t\u00e9 appliqu\u00e9s dans les deux \u00e9tudes, ce qui conf\u00e8re une grande certitude que les modifications anatomiques observ\u00e9es refl\u00e8tent une v\u00e9ritable inversion biologique plut\u00f4t que des artefacts technologiques.5<\/sup><\/p>\n\n\n\n\n\n\n\n\n
Segment art\u00e9riel<\/strong><\/td>\nInterpr\u00e9tation QCA 2014 (estimation visuelle %DS)<\/strong><\/td>\nInterpr\u00e9tation QCA 2018 (estimation visuelle %DS)<\/strong><\/td>\nVariation induite de la MLD (\u0394 mm)<\/strong><\/td>\nR\u00e9gression Classification<\/strong><\/td>\n<\/tr>\n<\/thead>\n
IVA proximale<\/td>\nSt\u00e9nose mod\u00e9r\u00e9e (40\u201355%)<\/td>\nSt\u00e9nose l\u00e9g\u00e8re (20\u201330%)<\/td>\nImportant<\/td>\nR\u00e9gression partielle<\/td>\n<\/tr>\n
Moyen-IVA<\/td>\nSt\u00e9nose l\u00e9g\u00e8re (20\u201330%)<\/td>\nPermeabilit\u00e9 quasi normale (<10%)<\/td>\nImportant<\/td>\nR\u00e9gression fonctionnelle compl\u00e8te<\/td>\n<\/tr>\n
Origine de la premi\u00e8re branche diagonale<\/td>\nSt\u00e9nose s\u00e9v\u00e8re (60\u201375%)<\/td>\nBrevet complet (<10%)<\/td>\nProfond<\/td>\nInversion anatomique compl\u00e8te<\/td>\n<\/tr>\n
Art\u00e8re circonflexe (segment moyen)<\/td>\nR\u00e9tr\u00e9cissement l\u00e9ger\/mod\u00e9r\u00e9 (30\u201345%)<\/td>\nAm\u00e9lioration de la perm\u00e9abilit\u00e9 (<20%)<\/td>\nMod\u00e9r\u00e9<\/td>\nR\u00e9gression partielle<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

B. Analyse des segments standardis\u00e9s et de la maladie diffuse<\/h4>\n

Les coches rouges visibles sur l'image confirment que l'analyse a utilis\u00e9 des \u201c segments de longueur identique \u00e9talonn\u00e9s et standardis\u00e9s \u201d. Cette technique est essentielle car elle permet de mesurer la variation du diam\u00e8tre luminal moyen (ALD) sur toute la longueur d'un segment, fournissant ainsi une mesure de inversion d'une maladie diffuse<\/strong>, indiquant une r\u00e9duction g\u00e9n\u00e9ralis\u00e9e de la charge de plaque, plut\u00f4t qu'une simple am\u00e9lioration focale au point le plus \u00e9troit.3<\/sup> L'\u00e9largissement vasculaire g\u00e9n\u00e9ralis\u00e9 observ\u00e9 entre les lignes rouges \u00e0 travers les segments de l'IVA et de la circonflexe sur l'image de 2018 confirme que le traitement syst\u00e9mique a induit avec succ\u00e8s la r\u00e9version de l'ath\u00e9roscl\u00e9rose diffuse.<\/p>\n

III. Analyse angiographique comparative d\u00e9taill\u00e9e (2014 vs. 2018)<\/h3>\n

La comparaison r\u00e9v\u00e8le une transformation morphologique remarquable et g\u00e9n\u00e9ralis\u00e9e, coh\u00e9rente avec une r\u00e9mission de la maladie r\u00e9ussie et prolong\u00e9e.<\/p>\n

A. Pourcentage estim\u00e9 de r\u00e9gression des segments art\u00e9riels coronaires<\/h4>\n

Le tableau suivant pr\u00e9sente la variation estim\u00e9e en pourcentage du calibre (pourcentage de st\u00e9nose du diam\u00e8tre, ou %DS) pour les segments cl\u00e9s, calcul\u00e9e \u00e0 partir d'une comparaison visuelle et en se basant sur une m\u00e9thodologie QCA de haute fid\u00e9lit\u00e9.<\/p>\n

B. Inf\u00e9rence qualitative et quantitative de la r\u00e9gression multifocale<\/h4>\n
    \n
  1. Inversion de branche diagonale :<\/strong> En 2014, la premi\u00e8re ramification diagonale (cercle rouge) pr\u00e9sentait une st\u00e9nose s\u00e9v\u00e8re de haut grade (r\u00e9duction du diam\u00e8tre estim\u00e9e entre 60% et 75%). Lors du suivi de 2018, ce segment est \u201ctotalement brevet\u00e9<\/strong>,\u201d, ce qui indique une r\u00e9duction probablement inf\u00e9rieure \u00e0 10% pour atteindre 20%. L\u2019ampleur de cette r\u00e9gression \u2014 soit une variation pouvant atteindre 65 points de pourcentage \u2014 correspond \u00e0 la r\u00e9gression r\u00e9ussie d\u2019une plaque ath\u00e9roscl\u00e9reuse tr\u00e8s vuln\u00e9rable et riche en lipides.6<\/sup> Les plaques riches en lipides et en contenu inflammatoire r\u00e9pondent tr\u00e8s bien au traitement intensif, tandis que les l\u00e9sions calcifi\u00e9es ou fibrotiques denses sont r\u00e9fractaires \u00e0 la r\u00e9gression.6<\/sup><\/li>\n
  2. \u00c9largissement g\u00e9n\u00e9ralis\u00e9 de l'IVA et de la circonflexe :<\/strong> L'\u00e9largissement coh\u00e9rent sur l'ensemble des segments standardis\u00e9s des vaisseaux IVA et circonflexe indique une r\u00e9duction de la charge ath\u00e9romateuse diffuse \u00e0 travers la paroi art\u00e9rielle, repr\u00e9sentant remodelage art\u00e9riel positif<\/strong>.8<\/sup> Cette am\u00e9lioration g\u00e9n\u00e9ralis\u00e9e exclut comme cause une intervention m\u00e9canique (telle qu'une pose d'stent ou une angioplastie), qui entra\u00eenerait des am\u00e9liorations hautement focales.1<\/sup> De plus, l'absence de dilatation anormale exclut une dilatation pathologique telle qu'une ectasie coronaire.9<\/sup><\/li>\n<\/ol>\n

    IV. Physiopathologie et implication th\u00e9rapeutique<\/h3>\n

    Les modifications angiographiques spectaculaires r\u00e9sultent de changements m\u00e9taboliques et structurels profonds au sein de la paroi art\u00e9rielle, atteignant un \u00e9tat de r\u00e9duction nette du volume de l'ath\u00e9rome.10<\/sup><\/p>\n

    A. M\u00e9canismes \u00e0 l'origine de la r\u00e9duction du volume de l'ath\u00e9rome<\/h4>\n

    La r\u00e9gression de la plaque est stimul\u00e9e par des m\u00e9canismes biologiques de gu\u00e9rison sp\u00e9cifiques, principalement la r\u00e9duction nette du volume pour cent d'ath\u00e9rome (PAV).10<\/sup> Les m\u00e9canismes cl\u00e9s comprennent l'augmentation de la capacit\u00e9 d'efflux du cholest\u00e9rol des cellules spumeuses et l'\u00e9limination des fragments de cellules n\u00e9crotiques contenus dans le c\u0153ur de la plaque, ce qui entra\u00eene une r\u00e9duction physique de la plaque.7<\/sup> Ce processus n\u00e9cessite que l'environnement th\u00e9rapeutique atteigne un \u00e9tat o\u00f9 le taux d'\u00e9limination du cholesterol de la paroi art\u00e9rielle augmente de mani\u00e8re significative surpasse<\/em> le taux de d\u00e9p\u00f4t, cr\u00e9ant une accumulation nette n\u00e9gative et soutenue du volume de plaque.11<\/sup><\/p>\n

    B. Corr\u00e9lation th\u00e9rapeutique : Modification intensive du mode de vie<\/h4>\n

    L'ampleur et le profil de la r\u00e9versibilit\u00e9 \u2014 une am\u00e9lioration g\u00e9n\u00e9ralis\u00e9e de plusieurs vaisseaux avec la r\u00e9solution compl\u00e8te d'une l\u00e9sion grave et potentiellement instable \u2014 constituent un r\u00e9sultat caract\u00e9ristique de modalit\u00e9s th\u00e9rapeutiques hautement efficaces. Ce niveau de gu\u00e9rison biologique est fortement associ\u00e9 \u00e0 la mise en \u0153uvre de Modification intensive du mode de vie<\/strong> programmes.10<\/sup><\/p>\n

    Ces programmes, souvent inspir\u00e9s du programme de m\u00e9decine du mode de vie d'Ornish, exigent une rigueur qui va au-del\u00e0 des directives conventionnelles et comprennent g\u00e9n\u00e9ralement 10<\/sup>:<\/p>\n

      \n
    • Une alimentation \u00e0 base d'aliments complets et v\u00e9g\u00e9taux, tr\u00e8s pauvre en graisses et en sucre.11<\/sup><\/li>\n
    • Exercice physique mod\u00e9r\u00e9 et r\u00e9gulier.<\/li>\n
    • Techniques structur\u00e9es de gestion du stress (par exemple, le yoga et la m\u00e9ditation).<\/li>\n
    • Soutien social renforc\u00e9 pour garantir l'adh\u00e9sion \u00e0 long terme.<\/li>\n<\/ul>\n

      L'observation d'une r\u00e9gression soutenue et profonde au cours de l'intervalle de quatre ans entre 2014 et 2018 constitue une preuve objective d'une conformit\u00e9 soutenue \u00e0 un tel r\u00e9gime rigoureux et intensif.10<\/sup><\/p>\n

      V. Pronostic clinique<\/h3>\n

      L'obtention d'une r\u00e9gression angiographique se traduit directement par une r\u00e9duction du risque d'\u00e9v\u00e9nements cardiovasculaires ind\u00e9sirables majeurs (MACE) futurs.<\/p>\n

        \n
      • R\u00e9duction des risques :<\/strong> Une analyse de m\u00e9ta-r\u00e9gression a montr\u00e9 que chaque r\u00e9duction de 1% du pourcentage de volume ath\u00e9romateux (PAV) est associ\u00e9e \u00e0 une diminution de 20% du risque relatif de survenue d\u2019\u00e9v\u00e9nements cardiovasculaires majeurs (MACE).13<\/sup> \u00c9tant donn\u00e9 l'am\u00e9lioration visuelle prononc\u00e9e dans ce cas, la r\u00e9duction estim\u00e9e du PAV est substantielle, sugg\u00e9rant un passage significatif d'un profil ath\u00e9rosclerotique \u00e0 haut risque (2014) \u00e0 un profil stabilis\u00e9 et \u00e0 risque extr\u00eamement faible (2018).13<\/sup><\/li>\n
      • Stabilisation de la plaque<\/strong> La r\u00e9gression signifie que les l\u00e9sions riches en lipides, auparavant instables et sujettes \u00e0 la rupture, ont \u00e9t\u00e9 biologiquement stabilis\u00e9es et structurellement r\u00e9duites. Cette stabilisation est le principal moteur du b\u00e9n\u00e9fice pronostique \u00e0 long terme.6<\/sup><\/li>\n<\/ul>\n

        R\u00e9f\u00e9rences<\/h3>\n
          \n
        1. Ibanez B, Fern\u00e1ndez-Ortiz A, Fern\u00e1ndez-Friera L, Garc\u00eda-Lunar I, Andr\u00e9s V, Fuster V. Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7\/8.\u00a0J Am Coll Cardiol<\/i>. 2021;78(2):156-179. doi:10.1016\/j.jacc.2021.05.011<\/li>\n
        2. Superko HR, Krauss RM. R\u00e9gression de la maladie coronarienne. Preuve convaincante du b\u00e9n\u00e9fice d'une prise en charge agressive des lipoprot\u00e9ines.\u00a0Trafic<\/i>. 1994;90(2):1056-1069. doi:10.1161\/01.cir.90.2.1056<\/li>\n
        3. Garrone P, Biondi-Zoccai G, Salvetti I, et al. L'angiographie coronaire quantitative \u00e0 l'\u00e8re actuelle : principes et applications.\u00a0Journal d'intervention cardiologique<\/i>. 2009;22(6):527-536. doi:10.1111\/j.1540-8183.2009.00491.x<\/li>\n
        4. Fencil LE, Doi K, Hoffman KR. Analyse pr\u00e9cise de la taille des vaisseaux sanguins et des l\u00e9sions st\u00e9notiques \u00e0 l'aide d'un syst\u00e8me d'angiographie soustractive num\u00e9rique (DSA) st\u00e9r\u00e9oscopique.\u00a0Invest Radiol<\/i>. 1988;23(1):33-41. doi:10.1097\/00004424-198801000-00008<\/li>\n
        5. Popma JJ, Lansky AJ, Yeh W, et al. Fiabilit\u00e9 des mesures angiographiques quantitatives dans le registre NACI (New Approaches to Coronary Intervention) : comparaison des lectures des centres cliniques et des lectures r\u00e9p\u00e9t\u00e9es du laboratoire central d'angiographie.\u00a0Am J Cardiol<\/i>. 1997;80(10A):19K-25K. doi:10.1016\/s0002-9149(97)00761-3<\/li>\n
        6. Lionakis N, Briasoulis A, Zouganeli V, et al. An\u00e9vrysmes des art\u00e8res coronaires : revue compl\u00e8te et pr\u00e9sentation d'un cas d'an\u00e9vrysme du tronc commun de la coronaires gauche.\u00a0Curr Probl Cardiol<\/i>. 2023;48(7):101700. doi:10.1016\/j.cpcardiol.2023.101700<\/li>\n
        7. Henzel J, K\u0119pka C, Kruk M, et al. R\u00e9gression de la plaque coronaire \u00e0 haut risque apr\u00e8s une intervention intensive sur le mode de vie dans la maladie coronaire non obstructive : une \u00e9tude randomis\u00e9e.\u00a0JACC Cardiovasc Imaging<\/i>. 2021;14(6):1192-1202. doi:10.1016\/j.jcmg.2020.10.019<\/li>\n
        8. Barrett TJ. Les macrophages dans la r\u00e9gression de l'ath\u00e9roscl\u00e9rose.\u00a0Arteriosclerosis, Thrombosis, and Vascular Biology<\/i>. 2020;40(1):20-33. doi:10.1161\/ATVBAHA.119.312802<\/li>\n
        9. Ueki Y, Itagaki T, Kuwahara K. Th\u00e9rapie hypolip\u00e9miante et r\u00e9gression de la plaque coronaire.\u00a0J Atheroscler Thromb<\/i>. 2024;31(11):1479-1495. doi:10.5551\/jat.RV22024<\/li>\n
        10. Ornish D, Scherwitz LW, Billings JH, et al. Changements de mode de vie intensifs pour la r\u00e9versibilit\u00e9 de la coronaropathie.\u00a0JAMA<\/i>. 1998;280(23):2001-2007. doi:10.1001\/jama.280.23.2001<\/li>\n
        11. Gould KL, Ornish D, Scherwitz L, et al. Changes in myocardial perfusion abnormalities by positron emission tomography after long-term, intense risk factor modification.\u00a0JAMA<\/i>. 1995;274(11):894-901. doi:10.1001\/jama.1995.03530110056036<\/li>\n
        12. Shishikura D, Kataoka Y, Di Giovanni G, et al. Progression of ultrasound plaque attenuation and low echogenicity associates with major adverse cardiovascular events.\u00a0Eur Heart J<\/i>. 2020;41(31):2965-2973. doi:10.1093\/eurheartj\/ehaa173<\/li>\n
        13. \u00a0<\/span>Brieger D, Pocock SJ, Blankenberg S, et al. R\u00e9sultats \u00e0 deux ans chez des patients stables \u00e0 haut risque apr\u00e8s un infarctus aigu du myocarde. Donn\u00e9es d'un registre mondial dans 25 pays.\u00a0Int J Cardiol<\/i>. 2020;311:7-14. doi:10.1016\/j.ijcard.2020.01.070<\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"

          L'ath\u00e9roscl\u00e9rose est une affection vasculaire chronique et progressive, dont la prise en charge repose traditionnellement sur des interventions visant \u00e0 ralentir sa progression.1 Le renversement mesurable de cette affection \u2014 d\u00e9fini comme une r\u00e9gression structurelle \u2014 constitue le meilleur r\u00e9sultat th\u00e9rapeutique dans la prise en charge des maladies cardiovasculaires.2 La r\u00e9gression est mise en \u00e9vidence par angiographie par une augmentation du diam\u00e8tre luminal minimal (DLM) ou une diminution du pourcentage de st\u00e9nose du diam\u00e8tre ( %DS ).<\/p>","protected":false},"author":16,"featured_media":8398,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[218,221,223,224],"tags":[],"class_list":["post-8395","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exercise-athletes-and-aging","category-peters-journey-and-records","category-plaque-arteries-and-disease","category-regression-and-reversal"],"acf":[],"yoast_head":"\nExpert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018) - The Premiere Heart Health Education Platform<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.curingheartdisease.com\/fr\/evaluation-angiographique-specialisee-de-la-regression-de-la-coronaropathie-serie-dangiographies-megdal-2014-2018\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018) - The Premiere Heart Health Education Platform\" \/>\n<meta property=\"og:description\" content=\"Atherosclerosis is a chronic, progressive vascular condition traditionally managed by interventions aimed at slowing its advancement.1 The measurable reversal of this condition\u2014defined as structural regression\u2014is the highest therapeutic outcome in cardiovascular disease management.2 Regression is evidenced angiographically by an increase in Minimal Lumen Diameter (MLD) or a decrease in Percent Diameter Stenosis ( %DS ).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.curingheartdisease.com\/fr\/evaluation-angiographique-specialisee-de-la-regression-de-la-coronaropathie-serie-dangiographies-megdal-2014-2018\/\" \/>\n<meta property=\"og:site_name\" content=\"The Premiere Heart Health Education Platform\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/curingheartdisease\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-26T14:48:33+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-16T15:04:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-11.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Peter Megdal PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@RMHDInc\" \/>\n<meta name=\"twitter:site\" content=\"@RMHDInc\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Peter Megdal PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/\"},\"author\":{\"name\":\"Peter Megdal PhD\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\"},\"headline\":\"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018)\",\"datePublished\":\"2025-07-26T14:48:33+00:00\",\"dateModified\":\"2026-07-16T15:04:38+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/\"},\"wordCount\":1423,\"publisher\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-11.jpg\",\"articleSection\":[\"Exercise, Athletes and Aging\",\"Peter's Journey and Records\",\"Plaque, Arteries and Disease\",\"Regression and Reversal\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/\",\"name\":\"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018) - The Premiere Heart Health Education Platform\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-11.jpg\",\"datePublished\":\"2025-07-26T14:48:33+00:00\",\"dateModified\":\"2026-07-16T15:04:38+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-11.jpg\",\"contentUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/post-image-11.jpg\",\"width\":1200,\"height\":630},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.curingheartdisease.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#website\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/\",\"name\":\"The Premiere Heart Health Education Platform\",\"description\":\"To make available to the public the state of the art information on how to reverse heart disease. This is an evidence-based organization utilizing the best available science, including diet, exercise drugs, and other resources to best fight this disease.\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.curingheartdisease.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\",\"name\":\"Curing Heart Disease, LLC\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/cropped-Curing-Heart-icon-red.png\",\"contentUrl\":\"https:\\\/\\\/www.curingheartdisease.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/cropped-Curing-Heart-icon-red.png\",\"width\":512,\"height\":512,\"caption\":\"Curing Heart Disease, LLC\"},\"image\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/curingheartdisease\",\"https:\\\/\\\/x.com\\\/RMHDInc\",\"https:\\\/\\\/www.instagram.com\\\/rmhdinc\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCm8dh9c_D5RfJL7Z1f-yY4w\"],\"description\":\"Curing Heart Disease, LLC is an independent cardiovascular health education organization that publishes evidence-based articles, videos, podcasts, and educational tools about cardiovascular disease prevention, lipid science, nutrition, exercise, and related health topics.\",\"founder\":{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\",\"name\":\"Peter Megdal, PhD\"},\"foundingPerson\":{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\",\"name\":\"Peter Megdal, PhD\"},\"knowsAbout\":[\"Cardiovascular health\",\"Cardiovascular disease prevention\",\"Heart disease education\",\"Nutrition\",\"Exercise\",\"Lipid science\",\"Atherosclerosis\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#\\\/schema\\\/person\\\/1468f3f6d05d6929d0583938c1236e53\",\"name\":\"Peter Megdal, PhD\",\"url\":\"https:\\\/\\\/www.curingheartdisease.com\\\/peters-story\\\/\",\"givenName\":\"Peter\",\"familyName\":\"Megdal\",\"honorificSuffix\":\"PhD\",\"jobTitle\":\"Nutrition Researcher and Cardiovascular Health Educator\",\"description\":\"Peter Megdal, PhD, is a nutrition researcher, cardiovascular health educator, published researcher, and longtime competitive cyclist. He earned a PhD in nutrition from the University of Massachusetts and publishes evidence-based cardiovascular health education through Curing Heart Disease.\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/peters-story\\\/\"},\"worksFor\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"affiliation\":{\"@id\":\"https:\\\/\\\/www.curingheartdisease.com\\\/#organization\"},\"alumniOf\":{\"@type\":\"CollegeOrUniversity\",\"name\":\"University of Massachusetts\"},\"knowsAbout\":[\"Nutrition\",\"Cardiovascular health education\",\"Cardiovascular disease prevention\",\"Lipid science\",\"Exercise physiology\",\"Scientific research\"],\"sameAs\":[\"https:\\\/\\\/www.curingheartdisease.com\\\/author\\\/peter-megdal\\\/\",\"https:\\\/\\\/www.linkedin.com\\\/in\\\/peter-megdal-56075a2\\\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u00c9valuation angiographique experte de la r\u00e9gression de la maladie coronarienne : l'angiogramme s\u00e9riel de Megdal (2014-2018) - La premi\u00e8re plateforme d'\u00e9ducation sur la sant\u00e9 cardiaque","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.curingheartdisease.com\/fr\/evaluation-angiographique-specialisee-de-la-regression-de-la-coronaropathie-serie-dangiographies-megdal-2014-2018\/","og_locale":"fr_FR","og_type":"article","og_title":"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018) - The Premiere Heart Health Education Platform","og_description":"Atherosclerosis is a chronic, progressive vascular condition traditionally managed by interventions aimed at slowing its advancement.1 The measurable reversal of this condition\u2014defined as structural regression\u2014is the highest therapeutic outcome in cardiovascular disease management.2 Regression is evidenced angiographically by an increase in Minimal Lumen Diameter (MLD) or a decrease in Percent Diameter Stenosis ( %DS ).","og_url":"https:\/\/www.curingheartdisease.com\/fr\/evaluation-angiographique-specialisee-de-la-regression-de-la-coronaropathie-serie-dangiographies-megdal-2014-2018\/","og_site_name":"The Premiere Heart Health Education Platform","article_publisher":"https:\/\/www.facebook.com\/curingheartdisease","article_published_time":"2025-07-26T14:48:33+00:00","article_modified_time":"2026-07-16T15:04:38+00:00","og_image":[{"width":1200,"height":630,"url":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-11.jpg","type":"image\/jpeg"}],"author":"Peter Megdal PhD","twitter_card":"summary_large_image","twitter_creator":"@RMHDInc","twitter_site":"@RMHDInc","twitter_misc":{"\u00c9crit par":"Peter Megdal PhD","Dur\u00e9e de lecture estim\u00e9e":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#article","isPartOf":{"@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/"},"author":{"name":"Peter Megdal PhD","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53"},"headline":"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018)","datePublished":"2025-07-26T14:48:33+00:00","dateModified":"2026-07-16T15:04:38+00:00","mainEntityOfPage":{"@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/"},"wordCount":1423,"publisher":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"image":{"@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#primaryimage"},"thumbnailUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-11.jpg","articleSection":["Exercise, Athletes and Aging","Peter's Journey and Records","Plaque, Arteries and Disease","Regression and Reversal"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/","url":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/","name":"\u00c9valuation angiographique experte de la r\u00e9gression de la maladie coronarienne : l'angiogramme s\u00e9riel de Megdal (2014-2018) - La premi\u00e8re plateforme d'\u00e9ducation sur la sant\u00e9 cardiaque","isPartOf":{"@id":"https:\/\/www.curingheartdisease.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#primaryimage"},"image":{"@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#primaryimage"},"thumbnailUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-11.jpg","datePublished":"2025-07-26T14:48:33+00:00","dateModified":"2026-07-16T15:04:38+00:00","breadcrumb":{"@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#primaryimage","url":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-11.jpg","contentUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2025\/12\/post-image-11.jpg","width":1200,"height":630},{"@type":"BreadcrumbList","@id":"https:\/\/www.curingheartdisease.com\/expert-angiographic-evaluation-of-coronary-artery-disease-regression-the-megdal-serial-angiogram-2014-2018\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.curingheartdisease.com\/"},{"@type":"ListItem","position":2,"name":"Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014\u20132018)"}]},{"@type":"WebSite","@id":"https:\/\/www.curingheartdisease.com\/#website","url":"https:\/\/www.curingheartdisease.com\/","name":"La premi\u00e8re plateforme d'\u00e9ducation sur la sant\u00e9 cardiaque","description":"Mettre \u00e0 la disposition du public les informations les plus r\u00e9centes sur la mani\u00e8re d'inverser les maladies cardiaques. Il s'agit d'une organisation fond\u00e9e sur des donn\u00e9es probantes qui utilise la meilleure science disponible, notamment le r\u00e9gime alimentaire, l'exercice physique, les m\u00e9dicaments et d'autres ressources pour lutter au mieux contre cette maladie.","publisher":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.curingheartdisease.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/www.curingheartdisease.com\/#organization","name":"Curing Heart Disease, LLC","url":"https:\/\/www.curingheartdisease.com\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/logo\/image\/","url":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2026\/06\/cropped-Curing-Heart-icon-red.png","contentUrl":"https:\/\/www.curingheartdisease.com\/wp-content\/uploads\/2026\/06\/cropped-Curing-Heart-icon-red.png","width":512,"height":512,"caption":"Curing Heart Disease, LLC"},"image":{"@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/curingheartdisease","https:\/\/x.com\/RMHDInc","https:\/\/www.instagram.com\/rmhdinc\/","https:\/\/www.youtube.com\/channel\/UCm8dh9c_D5RfJL7Z1f-yY4w"],"description":"Curing Heart Disease, LLC est une organisation ind\u00e9pendante d'\u00e9ducation \u00e0 la sant\u00e9 cardiovasculaire qui publie des articles, des vid\u00e9os, des podcasts et des outils \u00e9ducatifs fond\u00e9s sur des donn\u00e9es probantes concernant la pr\u00e9vention des maladies cardiovasculaires, la science des lipides, la nutrition, l'exercice physique et des sujets de sant\u00e9 connexes.","founder":{"@type":"Person","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53","name":"Peter Megdal, PhD"},"foundingPerson":{"@type":"Person","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53","name":"Peter Megdal, PhD"},"knowsAbout":["Cardiovascular health","Cardiovascular disease prevention","Heart disease education","Nutrition","Exercise","Lipid science","Atherosclerosis"]},{"@type":"Person","@id":"https:\/\/www.curingheartdisease.com\/#\/schema\/person\/1468f3f6d05d6929d0583938c1236e53","name":"Peter Megdal, PhD","url":"https:\/\/www.curingheartdisease.com\/peters-story\/","givenName":"Peter","familyName":"Megdal","honorificSuffix":"PhD","jobTitle":"Nutrition Researcher and Cardiovascular Health Educator","description":"Peter Megdal, PhD est chercheur en nutrition, formateur en sant\u00e9 cardiovasculaire, auteur de publications scientifiques et cycliste de comp\u00e9tition de longue date. Titulaire d'un doctorat en nutrition de l'universit\u00e9 du Massachusetts, il diffuse des informations fond\u00e9es sur des donn\u00e9es scientifiques en mati\u00e8re de sant\u00e9 cardiovasculaire via le site \u00ab Curing Heart Disease \u00bb.","mainEntityOfPage":{"@id":"https:\/\/www.curingheartdisease.com\/peters-story\/"},"worksFor":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"affiliation":{"@id":"https:\/\/www.curingheartdisease.com\/#organization"},"alumniOf":{"@type":"CollegeOrUniversity","name":"University of Massachusetts"},"knowsAbout":["Nutrition","Cardiovascular health education","Cardiovascular disease prevention","Lipid science","Exercise physiology","Scientific research"],"sameAs":["https:\/\/www.curingheartdisease.com\/author\/peter-megdal\/","https:\/\/www.linkedin.com\/in\/peter-megdal-56075a2\/"]}]}},"_links":{"self":[{"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/posts\/8395","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/comments?post=8395"}],"version-history":[{"count":13,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/posts\/8395\/revisions"}],"predecessor-version":[{"id":12130,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/posts\/8395\/revisions\/12130"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/media\/8398"}],"wp:attachment":[{"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/media?parent=8395"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/categories?post=8395"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.curingheartdisease.com\/fr\/wp-json\/wp\/v2\/tags?post=8395"}],"curies":[{"name":"Bien jou\u00e9","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}