{"id":8231,"date":"2025-02-01T11:48:41","date_gmt":"2025-02-01T16:48:41","guid":{"rendered":"https:\/\/www.curingheartdisease.com\/?p=8231"},"modified":"2026-07-16T11:08:22","modified_gmt":"2026-07-16T15:08:22","slug":"inversione-dellaterosclerosi-coronarica-intuizioni-meccanicistiche-da-studi-sulluomo-e-sui-primati","status":"publish","type":"post","link":"https:\/\/www.curingheartdisease.com\/it\/reversal-of-coronary-atherosclerosis-mechanistic-insights-from-human-and-primate-studies\/","title":{"rendered":"Inversione dell'aterosclerosi coronarica: intuizioni meccanicistiche da studi su umani e primati"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"

L'aterosclerosi coronarica pu\u00f2 regredire in condizioni definite. Studi seriali di ecografia intravascolare (IVUS) e di angio-tomografia computerizzata coronarica (CCTA) mostrano che la riduzione intensiva del colesterolo LDL (LDL-C) tramite statine ad alto dosaggio, inibitori di PCSK9 e, in contesti selezionati, icosapent etile, pu\u00f2 ridurre il volume della placca. Paradossalmente, il lume arterioso rimane spesso invariato o pu\u00f2 persino restringersi a causa del rimodellamento inverso o costrittivo. Studi complementari sullo stile di vita, come lo studio Ornish, hanno dimostrato una regressione angiografica guidata principalmente dal miglioramento della funzione endoteliale e vasomotoria.<\/p>","protected":false},"author":16,"featured_media":8296,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[216,222,223,224],"tags":[],"class_list":["post-8231","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diet-and-nutrition","category-plant-based-diets","category-plaque-arteries-and-disease","category-regression-and-reversal"],"acf":[],"yoast_head":"\nReversal of Coronary Atherosclerosis: Mechanistic Insights from Human and Primate Studies - The Premiere Heart Health Education Platform<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.curingheartdisease.com\/it\/inversione-dellaterosclerosi-coronarica-intuizioni-meccanicistiche-da-studi-sulluomo-e-sui-primati\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Reversal of Coronary Atherosclerosis: Mechanistic Insights from Human and Primate Studies - The Premiere Heart Health Education Platform\" \/>\n<meta property=\"og:description\" content=\"Coronary atherosclerosis can regress under defined conditions. 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