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Centro de Investigación

Ejercicio, atletas y envejecimiento

Ciencia del rendimiento, adaptación cardíaca en atletas, los récords mundiales de Peter y el reloj del envejecimiento cardiovascular.

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Descubre por qué el riesgo de enfermedad cardíaca se acelera a medida que envejecemos. Aprende cómo el endurecimiento arterial, las células zombis y el colesterol acumulado impactan en tu corazón.
Conozca las causas, los factores de riesgo y la detección de la muerte súbita cardíaca en atletas jóvenes. Descubra cómo el uso rápido de un DEA y los planes de emergencia salvan vidas.
¿Puede el ejercicio extremo ocultar la enfermedad cardíaca? Descubra por qué los atletas de resistencia de toda la vida desarrollan placa coronaria silenciosa y por qué reducir la ApoB podría protegerlos
If you are a competitive endurance athlete over the age of 65, you are likely living through a frustrating biological mystery. You still have the drive. You are still putting in the long miles on your bike or hitting the trail for your morning run. But despite your hard work, your body seems to be changing in ways that don't feel fair.
Durante mucho tiempo, la mayoría de la gente creyó que la única forma de ayudar a su corazón era haciendo "cardio". Nos decían que saliéramos a caminar, corriéramos en caminadoras o montáramos en bicicleta. Estos son excelentes hábitos, pero son solo una parte de la historia. Pensemos en el cuerpo como si fuera un auto. Hacer ejercicio aeróbico (cardio) es como lavar el auto y mantener la pintura brillante. Se ve bien y ayuda a que el auto dure, pero si nunca abres el capó para revisar el motor, el auto no funcionará para siempre.
Imagina un automóvil deportivo de alta gama. Es elegante, brillante y está construido para ganar las carreras más duras. Por fuera, se ve perfecto. La gente se detiene y se queda mirándolo cuando pasa porque parece que pudiera alcanzar las 200 millas por hora. Pero en lo profundo del motor, hay un problema oculto. La línea de combustible —el tubo que lleva la gasolina al motor— está casi completamente tapada con mugre. El auto aún puede andar, pero no puede alcanzar su velocidad máxima. Si esa mugre sigue acumulándose, el motor eventualmente dejará de funcionar por completo.
Imagine you are running on your favorite trail. You are breathing hard, and your legs feel heavy. Suddenly, a runner with gray hair and a steady stride zips right past you. They look like they could keep that pace all day. It is a common sight today - "master athletes" in their 60s and 70s who are faster and fitter than people half their age.
Imagine a high-end sports car. It is sleek, shiny, and built to handle the toughest races. On the outside, it looks absolutely perfect. But deep inside the engine, there is a tiny fuel line that has started to rust. Normally, a "check engine" light would flash on the dashboard to warn the driver that something is wrong. However, in this car, someone has placed a thick piece of black tape over the light. The driver keeps pushing the car to its limits, feeling invincible, totally unaware that the engine is struggling. Suddenly - at 100 miles per hour - the engine stalls.
In this interview, an elite cyclist and PhD-trained researcher shares the story of discovering severe coronary artery disease despite appearing exceptionally healthy. What began as a small drop in cycling power led to an invasive angiogram, a stent, and the discovery of multiple arterial blockages.
Many people feel a deep fear when they hear the words "clogged arteries." We often think of our heart like the plumbing in an old house. We imagine that over time, the pipes get filled with thick gunk. In this simple view, if the pipes are clear, you are healthy. If the pipes are full of gunk, you are in big trouble. We assume that people who exercise a lot will have the cleanest pipes of all.
Imagina que tu cuerpo es una ciudad gigante y bulliciosa. Para que la ciudad funcione, necesita una tubería de agua principal y masiva para llevar energía y suministros a cada una de las casas. En tu cuerpo, esa "tubería principal" es un tubo gigante llamado aorta. Los doctores la llaman el "Gran Vaso" porque es la línea de energía más grande e importante de tu sistema.
Durante décadas, los médicos y los corredores compartieron una cómoda creencia: si corrías maratones, tu corazón era a prueba de balas. Esto se conocía como la "hipótesis de Bassler", la idea de que terminar una carrera de 26 millas te otorgaba un pase libre contra las enfermedades cardíacas. Sin embargo, a medida que las exploraciones cardíacas modernas mejoraron, los médicos se llevaron una sorpresa. Las mismas personas que estaban en mejor forma física en el planeta —maratonistas y ciclistas de toda la vida— a menudo mostraban más "óxido" o acumulación en los conductos de su corazón (arterias) que las personas que se sentaban en el sofá.
Most people think there’s one perfect diet for a long life. But emerging science suggests something far more interesting: the rules of healthy eating actually change as we age. What protects you at 45 may not protect you at 85. Longevity isn’t about sticking to the same nutrition plan forever — it’s about adapting to your body’s shifting biology. And according to new research, age 65 appears to be a major turning point.
The Hook: Deconditioning vs. Aging Many of us view the heart’s decline as an inevitable slide into obsolescence, but the reality is more hopeful. The heart is not a ticking time bomb of decay; it is an adaptable muscle waiting for the right stimulus. The landmark Dallas Bed Rest and Training Study proved that just 20 days of total inactivity aged the hearts of 20-year-olds by more than 30 chronological years.
The landscape of preventive cardiology has undergone a profound transformation with the emergence of subclinical imaging, specifically the quantification of coronary artery calcium (CAC). For decades, cardiovascular risk assessment relied almost exclusively on probabilistic models derived from population-wide observational data.
What Peter Megdal’s World Hour Record Reveals About Aging, Fitness, and Cardiovascular Recovery For decades, human athletic performance was assumed to follow a largely linear decline beginning in early adulthood. Conventional physiological models predicted that the cardiovascular system, pulmonary capacity, and skeletal muscle function would steadily deteriorate as cellular senescence accumulated.
If you’re an endurance athlete, you’ve probably had this moment: your fitness is undeniable—resting heart rate is low, VO₂ is high, your training log looks like a work of art—and then a blood test shows LDL (“bad cholesterol”) is higher than expected. That can feel unfair. It can also trigger a very specific fear: “If I take a statin, will I lose performance?”
Peter Megdal, PhD, was a man who lived and breathed health. He was not just a regular guy who went to the gym. He was a world-record-holding cyclist. His legs were like steel. His lungs could breathe in huge amounts of air. He looked like the picture of perfect health. If you saw him riding his bike, you would think he would live to be one hundred years old.
El calor dentro del velódromo subió como algo vivo, elevándose de setenta y cinco a ochenta grados Fahrenheit mientras la tarde del desierto presionaba contra las paredes curvas. Desde debajo de la pista de madera llegaba la respiración tenue y constante del sistema de aire acondicionado —un suspiro mecánico bajo los cimientos que vibraba levemente a través del cuadro de mi bicicleta. A seis mil pies sobre el nivel del mar, en el aire enrarecido de Aguascalientes, México, comencé a rodar.
It's the prestige metric on every fitness watch and a key benchmark for vitality. But does a high VO₂ max actually make you live longer? Or is it just a sign that you're already doing the right things? As a medical engineer (PhD) and lifelong athlete, I've studied the biology of performance for decades. The evidence is compelling, but it's also nuanced. Let's unpack the science: Correlation vs. Causation.
Health transformations often begin with a wake-up call — and for Peter Megdal, that call came from his own heart. After receiving a diagnosis that forced him to confront the state of his health, Peter began questioning everything he thought he knew about food, science, and wellness. What started as a personal effort to heal his heart evolved into a deeper mission to help others make informed, sustainable choices for lifelong vitality.
Can an elite athlete have heart disease? Short answer: yes. I’m a lifelong endurance cyclist—now 65 years old - with three national records and two world records. I once believed fitness was protection. Short answer: yes. I’m a lifelong endurance cyclist—now 65 years old—with three national records and two world records. I once believed fitness was protection. But heart disease doesn’t care how fit you are. This is how I went from five blocked arteries to another world record—and what athletes can do to protect their hearts.
What do people on social media mean by “ketosis,” and does it automatically mean “healthier”? Ketosis simply means your blood ketones (often β-hydroxybutyrate, βHB) are elevated because carbohydrate availability is low (fasting, very-low-carb diets) or because you ingested ketones.
Atherosclerosis is a chronic, progressive vascular condition traditionally managed by interventions aimed at slowing its advancement.1 The measurable reversal of this condition—defined as structural regression—is the highest therapeutic outcome in cardiovascular disease management.2 Regression is evidenced angiographically by an increase in Minimal Lumen Diameter (MLD) or a decrease in Percent Diameter Stenosis ( %DS ).
We all aspire to be winners, but what does it truly mean to be a winner? It’s often defined as someone who places first in a race or excels in a competition. However, winning can encompass much more than that. After a week of racing at the Masters National Championships in Milwaukee, Wisconsin, I believe I emerged as a winner with finishes of 2nd, 14th, and 5th place in various events organized by USA Cycling.
Q: Are endurance athletes really at higher risk for atrial fibrillation? A: Yes. Atrial fibrillation (AF) is common in the general population, with a lifetime risk of roughly 1 in 4 adults.¹ While moderate exercise protects cardiovascular health, long-term, high-volume endurance training is associated with significantly higher AF rates. Meta-analyses show endurance athletes have about 2.5–3.6× higher odds of AF than non-athletes.
Meet the "Masters Athlete." This is a person over age 50 who feels like they are in the prime of their life. They run long races, bike for hundreds of miles, and spend hours in the pool. To the outside world, they look like the picture of health. They have a slow, steady resting pulse and plenty of energy.
Does the risk of atherosclerosis increase as we age? Yes. Atherosclerosis is considered a disease of aging. The likelihood and severity of plaque buildup in the arteries increase with age, even when other risk factors such as smoking, high cholesterol, or hypertension are controlled.
Peter Megdal sets cycling world record Survivor of heart disease excels in shattering limits others may set for him. [Editor's note: The following article concludes coverage in The Dedham Times of the world record Peter Megdal of Dedham holds in men's cycling. He set the new mark for ages 60-64 of 47.43 kilometers (29.47 miles) traversed in one hour on Sept. 12 at the Bicentario Velodromo in Aguascalientes, Mexico.
Peter Megdal sets new world record in cycling by Scott Heald | The Dedham Times The Guinness Book of World Records contains some zany entries indeed. One of those, achieved four-plus decades ago by a well-regarded Dedhamite, Mike Weir, who would go on to become the town’s police chief, involved throwing a grape the longest distance into the mouth of another person.
Tuesday, September 12th, Peter Megdal broke the Mens age 60 – 64 world record for the hour. At the Bicentario Velodromo in Aguascalientes, Mexico, Peter completed 47.430 kilometers (29.47 miles) in an hour, old record was 47.360 kilometers set in 2021 by Jim McMnurray of New Zealand.
Three-time national record holder explains his approach to improving health by Scott Heald / The Dedham Times / January 13, 2023 A traditional Romanian proverb states, “A great ship asks for deep waters.” Perhaps anyone who attempts something objectively daunting, unafraid to pursue opportunities that may not be readily apparent, is the sort of person to whom the proverb alludes.
Everyone has goals; for some, it's just to get out of bed in the morning, and others may want to become astronauts and rocket to the moon or Mars. I have spent years trying to break a world record in cycling. The last four years have thrown curveballs at me- such as recovering from heart disease, a broken hip last year, and this year COVID! On September 27, 2022, I competed at the world cycling track championships in Carson, CA, to attempt a 2-kilometer world championship race. Unfortunately, I had a terrible race and, in the process, contracted COVID. I was probably infected at the time that I was racing, which could account for my poor performance. To make matters worse, I was also planning to attempt a world record in the hour time trial in Aguascalientes, Mexico on October 17th, just three weeks away. How could I do this after such a poor performance only three weeks earlier?!
After setting the para C5 national record in 2018, I set my goal to best the current world record for the 60+-year-old when I turned 60.
Training Didn’t Help. My name is Dr. Peter Megdal, and this is my story of curing heart disease. In 2010 I noticed a steep drop in my power output during races. Racing cyclists have power meters that are attached to our bikes so we can accurately measure how strong we are in training and competitions. I was 50 years old, and my coach and my friends all told me that this was because I was getting older, but I knew a 15% drop was pretty steep and not normal especially in just one or two years.
Aplicación de IA

Calculadora de riesgo cardíaco

Calculadora educativa de riesgo cardíaco basada en antecedentes familiares con información de puntuación H, ingreso visual de árbol genealógico e informes en PDF compartibles.

Lee por qué esta aplicación es tan importante aquí.