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Es gibt heute Hunderte von Apps für die Herzgesundheit auf dem Markt. Die meisten von ihnen tun dasselbe: Sie überwachen Ihr HerzfrequenzDie Herzfrequenz ist die Anzahl der Schläge, die Ihr Herz pro Minute ausführt., Ihre Schritte verfolgen, Ihren Schlaf messen und Ihnen sagen, dass Sie mehr Gemüse essen sollen. Einige der ausgefeilteren Geräte lassen sich mit Wearables verbinden und geben Ihnen eine Echtzeit-Messung Ihres Pulses. Einige wenige markieren sogar einen unregelmäßigen Herzschlag.

These are useful tools. But they are all answering the wrong question.

Heart rate monitors tell you what your heart is doing right now. What they cannot tell you — what no wearable on your wrist can ever tell you — is what your heart is likely to do in ten, twenty, or thirty years based on the genetic blueprint you inherited from your family. That question requires a completely different kind of tool. And until now, no app has been built to answer it properly.

Das ändert sich heute.

Wir präsentieren den Herz-Risiko-Rechner

Der Herzrisiko-Rechner ist jetzt auf Google Play verfügbar und stellt etwas wirklich Neues im Bereich der Herzgesundheits-Apps dar. Es ist kein Herzfrequenzmesser. Es ist kein Schrittzähler. Es ist kein Meditations-Timer oder ein BlutdruckBlutdruck ist die Kraft, mit der das Blut gegen Ihre Arterienwände drückt. Er wird als zwei Zahlen geschrieben, wie 120/80. Die obere Zahl ist der Druck, wenn sich Ihr Herz zusammenzieht, die untere, wenn es sich entspannt. log. It is the first app built specifically around the scientific framework of inherited cardiac risk — the Vererbter GefahrenkoeffizientThe Inherited Hazard Coefficient is a proprietary quantitative formula (H = Σ(R × W) / A) that weights each family member's cardiac event by degree of biological relationship, severity of the event, and age at which it occurred, producing a single numerical index of a person's inherited cardiac risk load. — developed through years of research and grounded in peer-reviewed literature published in Zirkulation, JAMA Cardiology, der European Heart Journal, und das Lanzette. [1], [2], [3], [4]

Die Kernerkenntnis hinter dieser App ist einfach, aber tiefgreifend: dein FamiliengeschichteFamily history means whether your close relatives developed heart disease, and how young they were when it happened. ist keine Ja-oder-Nein-Frage.

Standard heart RisikorechnerEin Risikorechner schätzt Ihre Wahrscheinlichkeit für einen Herzinfarkt oder Schlaganfall in den nächsten zehn Jahren ab und verwendet dabei Ihr Alter, Ihren Cholesterinspiegel, Ihren Blutdruck und einige weitere Angaben. — including the widely used Framingham-RisikoskoreThe Framingham Risk Score is a specific ten-year heart-attack-risk calculator built from the Framingham Heart Study's decades of data — the original tool that turned "risk factors" into a number. — ask whether you have a family history of heart disease. [5] Yes or no. That’s it. A grandparent dying of a HerzinfarktEin Herzinfarkt tritt auf, wenn die Blutversorgung eines Teils des Herzmuskels unterbrochen wird und dieser Muskel abstirbt. mit 82 und einem Geschwisterteil, das zusammenbricht vor plötzlicher HerztodPlötzlicher Herztod tritt auf, wenn das Herz abrupt stehen bleibt und die Person innerhalb von Minuten stirbt, oft ohne vorherige Warnung. at 39 both get the same checkbox. They are not the same thing. Not even close. And the research is unambiguous about this. [6]

Was diese App unterscheidet

Es fragt wer, nicht nur ob

Der Herzrisikorechner ordnet die Herzerkrankungen Ihrer Familie nach Verwandtschaftsgrad, Alter beim Auftreten des Ereignisses und Schweregrad des Ausgangs. Ein tödliches Ereignis bei einem Verwandter ersten GradesA biological family member who shares approximately 50 percent of an individual's genetic material, specifically parents, siblings, and children; cardiac events in first-degree relatives carry substantially more inherited risk signal than events in more distant relatives. at age 40 carries a fundamentally different inherited signal than a non-fatal event in a grandparent at age 75. The app captures that difference mathematically, using the Inherited Hazard Coefficient formula developed by Peter Megdal, PhD:

H = Σ (R × W) / A

Wobei R das BeziehungskoeffizientThe relation coefficient (R) is the numerical weight assigned to a family member in the Inherited Hazard Coefficient formula based on degree of biological relatedness: 0.5 for first-degree relatives such as parents and siblings, and 0.25 for second-degree relatives such as grandparents and aunts and uncles. (0,5 für Eltern und Geschwister, 0,25 für Großeltern sowie Tanten und Onkel), W ist das SchweregradgewichtungThe severity weight (W) is a numerical value assigned within the Inherited Hazard Coefficient formula to reflect how serious a relative's cardiac event was — for example, sudden cardiac death receiving a higher weight than a non-fatal, medically managed event. of the cardiac event, and A is the age at which the event occurred. This formula produces a Family History IndexThe Family History Index is the numerical output produced by the Inherited Hazard Coefficient formula; it summarizes the aggregate inherited cardiac signal across a person's family tree in a single score that can be used to guide screening decisions. that reflects the true inherited signal in your family tree — not a simplified checkbox that loses most of the information.

It Reveals the Imaging Trap

One of the most important — and most alarming — findings in recent cardiovascular research is what clinicians call the Imaging-TrapThe Imaging Trap is the clinical scenario in which a patient with significant inherited cardiac risk receives a zero Coronary Artery Calcium score and is falsely reassured, when in reality dangerous soft non-calcified plaque may already be present and detectable only by Coronary CT Angiography.. A standard Coronary ArterieEine Arterie ist ein Blutgefäß, das Blut vom Herzen weg in den Rest des Körpers transportiert. Ein Kalzium-Scan, eines der am häufigsten verwendeten Screening-Instrumente in der Kardiologie, kann selbst dann einen Wert von null ergeben, wenn gefährlicher weicher, nicht verkalkte PlaqueNicht verkalkter Plaque ist der weiche, fettige Teil eines Plaques, der nicht mit Calcium verhärtet ist. Er stellt sich in einem CT-Scan dunkel dar. is actively building in your arteries. [7] For people with a significant inherited cardiac risk, a zero calcium score is not reassurance. It is a false negative.

The 2025 CAUGHT-CAD randomized trial confirmed that in patients with a family history of premature coronary artery disease, Coronary CT Angiography — not standard calcium scoring — is required to detect non-calcified PlaquePlaque ist die Ansammlung von Cholesterin, Immunzellen, Narbengewebe und Kalzium in einer Arterienwand. and guide timely intervention. [8] The Heart Risk Calculator is built around this research. It helps you understand whether your family history pattern places you in the zone where standard imaging tools may be inadequate — and arms you with the right questions to bring to your physician.

Es erfasst, was Wearables völlig übersehen

Your Apple Watch knows your resting heart rate. It does not know that your brother had a fatal heart attack at 42. Your Fitbit tracks your sleep quality. It cannot tell you that a sibling with premature heart disease confers an odds ratio of 2.48 for your own cardiac risk — a figure documented in peer-reviewed research published in Zirkulation. [6] Your Garmin measures your VO2 maxVO2 max ist die maximale Sauerstoffmenge, die Ihr Körper bei maximaler Anstrengung nutzen kann. Es ist das Standardmaß für die kardiorespiratorische Fitness.. It has no way of accounting for the gene dosing effectThe gene dosing effect refers to the amplified probability of carrying a pathogenic cardiac variant when both parents have experienced early cardiac events; having two affected first-degree parents roughly doubles the inherited risk signal compared with one, raising the likelihood of a causative inherited mutation substantially. that occurs when both parents experienced early kardiale EreignisseKlinisch signifikante kardiovaskuläre Ereignisse – einschließlich Myokardinfarkt, instabiler Angina pectoris und Herztod –, die als Endpunkte in kardiovaskulären Studien verwendet werden., raising your probability of carrying a pathogene VarianteA pathogenic variant is a gene mutation that has been demonstrated to cause or substantially increase the risk of a specific disease; in the context of inherited cardiac risk, it refers to mutations in genes such as those underlying Familial Hypercholesterolemia that markedly elevate lifetime heart disease probability. to 25%. [9]

Wearables measure what is happening in your body right now. The Heart Risk Calculator measures what your genetic inheritance suggests about your lifetime cardiac trajectory. These are complementary tools, not competing ones — but only one of them is capturing the inherited signal that determines whether standard screening is sufficient for you.

Das gibt Ihnen etwas, das Sie zu Ihrem Arzt mitnehmen können

Every output from the Heart Risk Calculator is framed as a conversation starter, not a conclusion. The app generates a discussion-ready family history summary and a set of specific, clinically grounded questions you can bring to your next appointment. Questions like: given my family pattern, could I have soft plaque that a standard calcium scan would miss? Should I be referred to a PräventivkardiologeA preventive cardiologist is a physician subspecialist focused on identifying and modifying cardiovascular risk factors before a first event occurs, using advanced lipid testing, imaging, and genetic risk assessment rather than waiting for symptomatic disease. rather than managed in primary care? Does my family history change how standard risk tools should be interpreted in my case? [10]

Das sind die Fragen, die den Verlauf einer klinischen Untersuchung wirklich verändern können. Es sind die Fragen, die eine routinemäßige jährliche Untersuchung in ein bedeutsames kardiovaskuläres Gespräch verwandeln. Und es sind die Fragen, von denen die meisten Menschen gar nicht wissen, dass sie sie stellen können – weil noch nie jemand ihre Familienanamnese so aufbereitet hat, dass diese Fragen sichtbar werden.

Es basiert auf echter Wissenschaft

The Heart Risk Calculator is not a wellness app built on general advice. It is built on a framework supported by more than 40 peer-reviewed publications. The gene dosing model that underlies the Inherited Hazard Coefficient is grounded in foundational research on Familial HypercholesterolemiaFamiliäre Hypercholesterinämie, kurz FH, ist eine vererbte Erkrankung, bei der die Leber Cholesterin nicht richtig aus dem Blut entfernen kann. Die Werte sind von Geburt an sehr hoch. veröffentlicht in Nature Reviews, Lanzette, und das European Heart Journal. [9] The sibling risk data comes from landmark studies in Zirkulation und JAMA Cardiology. [6] The clinical significance of early cardiac events in close relatives — and the inadequacy of standard tools in capturing that significance — is documented across decades of cardiovascular EpidemiologieEpidemiologie ist die Erforschung von Gesundheitstrends in großen Bevölkerungsgruppen – wer erkrankt, wo und was diese Personen gemeinsam hatten.. [10]

This is not an algorithm someone built in a weekend. It is an evidence-informed framework developed by a researcher who has spent years studying inherited cardiac risk and translating that research into something accessible to the people who need it most.

Warum das gerade jetzt von Bedeutung ist

Heart disease remains the number one cause of death in the United States. [11] Roughly half of all Americans have a family history of cardiac events. [12] And yet the tools available to most people for understanding their inherited risk remain remarkably primitive — a checkbox on an intake form, a Framingham score that was never designed to capture genetic loading, [5] and a calcium scan that may miss the most dangerous plaque entirely in younger, gene-dosed individuals. [7], [10]

For a 20-year-old whose sibling died of sudden cardiac death at 38, the Framingham Risk Score will often return a ten-year risk of under one percent — because the formula is driven by chronological age, not inherited biology. [5] That person is not low risk. They may be in the highest risk category of all. And without a tool that captures the inherited signal in their family history, they will never know to ask the right questions until it is too late.

Die Heart Risk App existiert für diese Person. Sie existiert für jeden, der in einem Sprechzimmer saß und gesagt hat “Ja, Herzerkrankungen kommen in meiner Familie vor” und dabei zugesehen hat, wie diese Information in einem Ankreuzkästchen verschwand, das nichts an seiner Behandlung ändert.

Laden Sie es noch heute herunter

Die App „Herzrisikorechner“ ist ab sofort bei Google Play für $4,99 erhältlich. Es handelt sich um ein Aufklärungsinstrument, nicht um ein Medizinprodukt, und es ersetzt keine klinische Untersuchung. Aber es könnten die wichtigsten fünf Dollar sein, die Sie für Ihre Herzgesundheit ausgeben – nicht, weil die App Ihren Puls misst, sondern weil sie endlich die Frage stellt, für deren Beantwortung Wearables und herkömmliche Rechner nie konzipiert wurden.

Ihre Familiengeschichte ist ein Datenbestand. Es ist Zeit, ihn zu nutzen.

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This tool is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before making health decisions. Research by Peter Megdal, PhD — CuringHeartDisease.com

Referenzen

1. D’Agostino RB Sr, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008;117(6):743-753. doi:10.1161/CIRCULATIONAHA.107.699579
2. Virani SS, Alonso A, Aparicio HJ, et al. Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association. Circulation. 2021;143(8):e254-e743. doi:10.1161/CIR.0000000000000950
3. Nordestgaard BG, Chapman MJ, Humphries SE, et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J. 2013;34(45):3478-90a. doi:10.1093/eurheartj/eht273
4. Ference BA, Ginsberg HN, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017;38(32):2459-2472. doi:10.1093/eurheartj/ehx144
5. D’Agostino RB Sr, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008;117(6):743-753. doi:10.1161/CIRCULATIONAHA.107.699579
6. Nasir K, Michos ED, Rumberger JA, et al. Coronary artery calcification and family history of premature coronary heart disease: sibling history is more strongly associated than parental history. Circulation. 2004;110(15):2150-2156. doi:10.1161/01.CIR.0000144464.11080.14
7. Villines TC, Hulten EA, Shaw LJ, et al. Prevalence and severity of coronary artery disease and adverse events among symptomatic patients with coronary artery calcification scores of zero undergoing coronary computed tomography angiography: results from the CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter) registry. J Am Coll Cardiol. 2011;58(24):2533-2540. doi:10.1016/j.jacc.2011.10.851
8. Nerlekar N, Vasanthakumar SA, Whitmore K, et al. Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease: A Randomized Clinical Trial. JAMA. 2025;333(16):1403-1412. doi:10.1001/jama.2025.0584
9. Nordestgaard BG, Chapman MJ, Humphries SE, et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J. 2013;34(45):3478-90a. doi:10.1093/eurheartj/eht273
10. Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;140(11):e596-e646. doi:10.1161/CIR.0000000000000678
11. Martin SS, Aday AW, Allen NB, et al. 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. Circulation. 2025;151(8):e41-e660. doi:10.1161/CIR.0000000000001303
12. Moonesinghe R, Yang Q, Zhang Z, Khoury MJ. Prevalence and Cardiovascular Health Impact of Family History of Premature Heart Disease in the United States: Analysis of the National Health and Nutrition Examination Survey, 2007-2014. J Am Heart Assoc. 2019;8(14):e012364. doi:10.1161/JAHA.119.012364