Author Archives: Peter Megdal PhD

For decades, we have been conditioned to view heart disease as a sudden catastrophe—a cardiac “lightning strike” that occurs in the sixth or seventh decade of life. In reality, atherosclerotic cardiovascular disease is a lifelong biological process, a silent passenger that boards the vessel in our youth. Despite mountains of “low-fat” dietary advice, heart disease remains the global leader in mortality.
Understanding Your Heart: High Cholesterol and Your Family History. The Big Picture: How Your Heart Stays Healthy. Think of your heart as the most important pump in your home, and your arteries as the "pipes" that carry life-sustaining blood to every room in your body. For the pump to work perfectly, those pipes need to stay clear and open.
Winning the Genetic Lottery: 3 Secrets Your DNA Reveals About a Healthy Heart. Introduction: The Mystery of the “Heart-Healthy” Gene. Why do some stay heart-healthy despite a poor diet? The answer lies in the “genetic lottery.” Scientists are decoding these mysteries using Mendelian randomization—the study of “experiments of nature.” These rare DNA variations act as natural off-switches, providing built-in shields against disease.
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