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VO₂ max: the deriminant of Health and Longevity?

It's the prestige metric on every fitness watch and a key benchmark for vitality. But does a high VO₂ max actually make you live longer? ...

Rethinking Heart Health: How Peter Megdal Turned a Diagnosis into a Mission for Change

Health transformations often begin with a wake-up call — and for Peter Megdal, that call came from his own heart. After receiving a diagnosis that ...

Heart Disease in Masters Athletes: How I Reversed My Artery Blockages and Set a World Record at 65

Can an elite athlete have heart disease? Short answer: yes. I’m a lifelong endurance cyclist—now 65 years old - with three national records and two ...

Nattokinase and Cardiovascular Plaque: What the Human Research Really Says

People want simple answers to complex problems. Atherosclerotic plaque—that fatty, inflammatory buildup inside artery walls—feels like something you should be able to “clean out” like ...

The Great Nutrition Debate: Evidence-Based Realities of Paleo/Keto/Caveman vs Whole food plant based diets for Longevity and Heart Disease

In a world of "biohacking" and rapid weight-loss trends, two dietary paradigms often clash: the Low-Fat Whole Food Plant-Based (WFPB) diet and the high-protein/high-fat Paleo/Ketogenic ...

Keto vs. Whole-Food Plant-Based: What’s the hard evidence for performance, insulin sensitivity, heart disease reversal, and longevity?

What do people on social media mean by “ketosis,” and does it automatically mean “healthier”? Ketosis simply means your blood ketones (often β-hydroxybutyrate, βHB) are ...

The Protein Debate

Dr. Loren Cordain vs. Dr. T. Colin Campbell Original context: Public nutrition debate from the mid-2000s reflecting two competing paradigms: evolutionary biology versus whole-diet epidemiology. ...

Treating heart disease with diet isn’t just a modern obsession – it’s a practice backed by millions of years of evolutionary history and the sharpest tools in modern science

To truly settle the long-running "cold war" between Dr. Loren Cordain’s Paleo camp and Dr. T. Colin Campbell’s plant-based paradigm, we have to look past ...

Expert Angiographic Evaluation of Coronary Artery Disease Regression: The Megdal Serial Angiogram (2014–2018)

Atherosclerosis is a chronic, progressive vascular condition traditionally managed by interventions aimed at slowing its advancement.1 The measurable reversal of this condition—defined as structural regression—is ...

Peter Megdal gets second at National Championships

We all aspire to be winners, but what does it truly mean to be a winner? It’s often defined as someone who places first in ...

The Plant-Based Paradox: Why Not All Veggie Diets Are Created Equal for Your Heart

For years, we've heard the chorus: "Eat more plants for a healthier heart!" And largely, that advice holds true. Numerous studies have championed the benefits ...

Can Diet Really Reverse Heart Disease?

​A Practical, Evidence-Based Q&A Inspired by the Ornish Debate ​Introduction: Why This Question Won’t Go Away ​Dean Ornish has claimed for decades that intensive lifestyle ...

Q&A: Can Your Love for Red Meat Be Dangerous?

Neu5Gc, Plant-Based Protection, and Atherosclerotic Heart Disease Q1. What is Neu5Gc, and why is it linked to heart disease? Neu5Gc (N-glycolylneuraminic acid) is a type ...

Q&A: Atrial Fibrillation, Endurance Training, and Ablation — What Athletes Need to Know

Q: Are endurance athletes really at higher risk for atrial fibrillation? A: Yes. Atrial fibrillation (AF) is common in the general population, with a lifetime ...

Cardiovascular Risk Management and Training Modification for the Masters Athlete (50+) with Treated Atrial Fibrillation: An Expert Report

Executive Summary: The Necessity of Training Modification The management of Atrial Fibrillation (Afib) in the Masters athlete (defined generally as age 35 and above, and ...

Q&A: Are Everyday Microplastics Fueling Heart Disease?

New research from the University of California, Riverside suggests microplastics may directly accelerate heart disease — especially in males. Here’s what the study uncovered, explained ...

Can Decreasing Homocysteine with L-Methylfolate + Active B-Vitamins Help Prevent Atherosclerosis and Reduce Plaque?

Cardiovascular prevention prioritizes proven interventions: cholesterol management, blood pressure control, smoking cessation, and lifestyle optimization. However, homocysteine is an additional modifiable risk factor—an amino acid ...

Coronary Plaque Regression, the Lumen Paradox, and Vascular Remodeling in Athletes: Integrating Pharmacologic and Whole-Food, Plant-Based Strategies

Background: Coronary atherosclerosis, long thought to be an inexorably progressive disease, is now recognized as biologically reversible under specific metabolic and inflammatory conditions. Imaging studies ...

How Does Age Affect Atherosclerosis? A Q&A Explainer

Does the risk of atherosclerosis increase as we age? Yes. Atherosclerosis is considered a disease of aging. The likelihood and severity of plaque buildup in ...

Reversal of Coronary Atherosclerosis: Mechanistic Insights from Human and Primate Studies

Coronary atherosclerosis can regress under defined conditions. Serial intravascular ultrasound (IVUS) and coronary computed tomography angiography (CCTA) studies show that intensive low-density lipoprotein cholesterol (LDL-C) ...
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