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Atherosclerotic cardiovascular disease (ASCVD) remains the leading global cause of mortality despite major advances in acute care. Modern preventive cardiology increasingly recognizes apolipoprotein B (ApoB)–containing ...
The clinical assessment of coronary artery calcium (CAC) has undergone a paradigm shift over the past three decades, evolving from a research tool to a ...
The landscape of preventive cardiology has undergone a profound transformation with the emergence of subclinical imaging, specifically the quantification of coronary artery calcium (CAC). For ...
For decades, the public has viewed heart disease as a “late-life accident”—a sudden collision of age and lifestyle that strikes in the golden years. ...
The menopausal transition is not simply a local shutdown of reproductive function; it is a far-reaching neuroendocrine reconfiguration marked by declining levels and unpredictable oscillations ...
Clinical Paradigms of Disease Resolution: Biological Differentiation between the Cure of Pathological Processes and the Reversal of Structural Damage The medical community has historically distinguished ...
Executive Summary: The Paradigm Shift in Acute Coronary Syndromes For much of modern cardiology, acute myocardial infarction (AMI) has been dominated by a “plumbing model”: ...
What Peter Megdal’s World Hour Record Reveals About Aging, Fitness, and Cardiovascular Recovery For decades, human athletic performance was assumed to follow a largely linear ...
The Bergström Study and the Paradigm Shift in Primary Prevention The publication of the Bergström et al. study in the Journal of the American Medical ...
Heart Disease and The Fish-Oil Confusion, the Vascepa Controversy, and What the Evidence Actually Shows For decades, cardiovascular medicine has been dominated by a single, ...
Apolipoprotein B, Imaging Resolution, and the Illusion of “Normal” Coronary Arteries at Age 60. The clinical assertion that individuals maintaining markedly elevated levels of low-density ...
If you’re an endurance athlete, you’ve probably had this moment: your fitness is undeniable—resting heart rate is low, VO₂ is high, your training log looks ...
Cardiovascular medicine is undergoing a substantive paradigm shift, moving from a predominantly reactive, symptom-driven model toward a preventive framework grounded in early detection and individualized ...
Can LDL Be Too Low? What PCSK9 Inhibitors Mean for Brain Health PCSK9 inhibitors are among the most powerful cholesterol-lowering treatments available. They can lower ...
Introduction: Challenging the Paradigm of Permanent Progression The management of coronary artery disease (CAD) has traditionally been viewed through the lens of “risk management.” In ...
The heat inside the velodrome rose like a living thing, swelling from seventy-five to eighty degrees Fahrenheit as the desert afternoon pressed against the curved ...
For decades, preventive cardiology has been anchored by a single, powerful concept: the "lipid hypothesis." We operated under the assumption that cholesterol accumulation—specifically LDL-C—was the ...